KDM3B Antibodies

AND KDM3B ELISA kits, KDM3B Proteins

Many biological assays use antibodies to detect KDM3B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KDM3B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KDM3B antibodies...

We validate the specificity of these antibodies to KDM3B by testing them on tissues known to express KDM3B positively and negatively. Browse below to find the KDM3B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KDM3B Infographic by Boster Bio

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Anti-JMJD1B KDM3B Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A08117
0.1 mg

KDM3B Overview

Facts about Lysine-specific demethylase 3B.

KDM3B 3D structure. Source: alphafold

Lysine-specific demethylase 3B (KDM3B)

Histone demethylase that especially demethylates'Lys- 9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate.

May have tumor suppressor activity. .

Gene Information

Human
Gene Name:	KDM3B
Uniprot:	Q7LBC6
Entrez:	51780

Family

Belongs to:

JHDM2 histone demethylase family

Alternative Names

C5orf7; EC 1.14.11; EC 1.14.11.-; JHDM2B; JmjC domain-containing histone demethylation protein 2B; JMJD1B; jumonji domain containing 1B; Jumonji domain-containing protein 1B; KIAA1082chromosome 5 open reading frame 7; lysine (K)-specific demethylase 3B; lysine-specific demethylase 3B; NET22,5qNCA; Nuclear protein 5qNCA

Molecular Weight

Mass (kDA):
191.581 kDA

Genomic Context


Human

Location:	5q31.2
Sequence:	5; NC_000005.10 (138352685..138437027)

Tissue Specificity

Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.

Subcellular Localizations

Nucleus.

Diseases

Malignant Neoplasms
Leukemia
Leukemia, Myelocytic, Acute
Myeloid Leukemia
Dysmyelopoietic Syndromes
Cell Invasion
Malignant Neoplasm Of Prostate
Leukemogenesis
Lung Neoplasms
Colonic Neoplasms
Acute Lymphocytic Leukemia
Neoplasm Invasiveness

Haploinsufficiency
Osteosarcoma
Prostatic Neoplasms
Neoplasms
Loss Of Chromosome 5
Loss Of Chromosome 5q
Acute Promyelocytic Leukemia

Pathways

Methylation
Demethylation
Cell Proliferation
Cell Migration
Cell Motility
Cell Differentiation
Histone Lysine Methylation

Histone Methylation
Chromatin Remodeling

PTMs

Methylation

Acetylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KDM3B

References

PMID: 11087669 by Lai F., et al. cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins.

PMID: 11687974 by Hu Z., et al. A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31.