KCNS3 Antibodies

AND KCNS3 ELISA kits, KCNS3 Proteins

Many biological assays use antibodies to detect KCNS3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNS3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNS3 antibodies...

We validate the specificity of these antibodies to KCNS3 by testing them on tissues known to express KCNS3 positively and negatively. Browse below to find the KCNS3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNS3 Infographic by Boster Bio

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Anti-KCNS3 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A10135
100ul

KCNS3 Overview

Facts about Potassium voltage-gated channel subfamily S member 3.

KCNS3 3D structure. Source: alphafold

Potassium voltage-gated channel subfamily S member 3 (KCNS3)

Potassium channel subunit that doesn't form functional channels alone. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 (PubMed:10484328).

Heterotetrameric channel activity formed with KCNB1 show increased current amplitude with the threshold for action potential activation shifted towards more negative values in hypoxic-treated pulmonary artery smooth muscle cells (By similarity). .

Gene Information

Human
Gene Name:	KCNS3
Uniprot:	Q9BQ31
Entrez:	3790

Family

Belongs to:

potassium channel family

Alternative Names

Potassium voltage-gated channel subfamily S member 3

Molecular Weight

Mass (kDA):
56.001 kDA

Genomic Context


Human

Location:	2p24.2
Sequence:	2; NC_000002.12 (17877847..17932961)

Tissue Specificity

Detected in whole normal term placental and placental chorionic plate arteries and veins. Detected in syncytiotrophoblast and in blood vessel endothelium within intermediate villi and chorionic plate (at protein level) (PubMed:22943705). Detected in most tissues, but not in peripheral blood lymphocytes. The highest levels of expression are in lung (PubMed:10484328).

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 (PubMed:10484328).

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNS3

References

PMID: 10484328 by Shepard A.R., et al. Electrically silent potassium channel subunits from human lens epithelium.

PMID: 22943705 by Fyfe G.K., et al. Expression of an electrically silent voltage-gated potassium channel in the human placenta.