KCNJ5 Antibodies

AND KCNJ5 ELISA kits, KCNJ5 Proteins

Many biological assays use antibodies to detect KCNJ5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNJ5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNJ5 antibodies...

We validate the specificity of these antibodies to KCNJ5 by testing them on tissues known to express KCNJ5 positively and negatively. Browse below to find the KCNJ5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: KCNJ6

KCNJ5 Infographic by Boster Bio

All KCNJ5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-KCNJ5/Kir3.4 Antibody

1 Q&As

Human, Mouse, Rat

ELISA, IF, ICC, WB

$335
Cat # A02160
100ul

KCNJ5 Overview

Facts about G protein-activated inward rectifier potassium channel 4.

KCNJ5 3D structure. Source: alphafold

G protein-activated inward rectifier potassium channel 4 (KCNJ5)

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.

Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Gene Information

Human
Gene Name:	KCNJ5
Uniprot:	P48544
Entrez:	3762

Family

Belongs to:

inward rectifier-type potassium channel (TC 1.A.2.1) family

Alternative Names

Cardiac inward rectifier; CIRKIR3.4; G protein-activated inward rectifier potassium channel 4; GIRK-4; GIRK4Kir3.4; Heart KATP channel; Inward rectifier K(+) channel Kir3.4; inward rectifier K+ channel KIR3.4; IRK-4; KATP-1; KATP1cardiac ATP-sensitive potassium channel; LQT13; Potassium channel, inwardly rectifying subfamily J member 5; potassium inwardly-rectifying channel, subfamily J, member 5

Molecular Weight

Mass (kDA):
47.668 kDA

Genomic Context


Human

Location:	11q24.3
Sequence:	11; NC_000011.10 (128891356..128921163)

Tissue Specificity

Islets, exocrine pancreas and heart. Expressed in the adrenal cortex, particularly the zona glomerulosa.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Hyperaldosteronism
Adenoma
Conn Syndrome
Hypertensive Disease
Hyperplasia
Neoplasms
Tumors Of Adrenal Cortex
Adrenal Gland Neoplasms
Cardiac Fibrillation
Cardiac Arrhythmia
Adrenal Cortical Adenoma
Infarction
Myocardial Infarction

Atrial Fibrillation
Malignant Neoplasm Of Adrenal Cortex
Adrenal Hyperplasia
Pheochromocytoma
Endocrine Hypertension
Obesity
Carcinoma

Pathways

Pathogenesis
Membrane Depolarization
Cell Proliferation
Secretion
Aldosterone Secretion
Insulin Secretion
Transport
Regulation Of Signaling
Reverse Transcription
Translation
Nutrient Import
Lipid Homeostasis
Diestrus

Bioluminescence
Membrane Hyperpolarization
Dna Repair
Ion Transport
Cortisol Secretion
Energy Homeostasis
Regulation Of Aldosterone Secretion

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNJ5

References

PMID: 8047164 by Ashford M.L.J., et al. Cloning and functional expression of a rat heart KATP channel.

PMID: 8558261 by Spauschus A., et al. A G-protein-activated inwardly rectifying K+ channel (GIRK4) from human hippocampus associates with other GIRK channels.