KCNJ14 Antibodies

AND KCNJ14 ELISA kits, KCNJ14 Proteins

Many biological assays use antibodies to detect KCNJ14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNJ14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNJ14 antibodies...

We validate the specificity of these antibodies to KCNJ14 by testing them on tissues known to express KCNJ14 positively and negatively. Browse below to find the KCNJ14 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNJ14 Infographic by Boster Bio

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Anti-IRK14 KCNJ14 Antibody

Human

ELISA, WB

$380
Cat # A13586
100ul

KCNJ14 Overview

Facts about ATP-sensitive inward rectifier potassium channel 14.

KCNJ14 3D structure. Source: alphafold

ATP-sensitive inward rectifier potassium channel 14 (KCNJ14)

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.

The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ14 gives rise to low-conductance channels with a low affinity to the channel blockers Barium and Cesium (By similarity).

Gene Information

Human
Gene Name:	KCNJ14
Uniprot:	Q9UNX9
Entrez:	3770

Family

Belongs to:

inward rectifier-type potassium channel (TC 1.A.2.1) family

Alternative Names

ATP-sensitive inward rectifier potassium channel 14

Molecular Weight

Mass (kDA):
47.846 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (48455574..48466980)

Tissue Specificity

Expressed preferentially in retina.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

PTMs

S-nitrosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KCNJ14

References

PMID: 10942728 by Hughes B.A., et al. Cloning and functional expression of human retinal Kir2.4, a pH- sensitive inwardly rectifying K+ channel.

PMID: 10723734 by Toepert C., et al. Cloning, structure and assignment to chromosome 19q13 of the human Kir2.4 inwardly rectifying potassium channel gene (KCNJ14).