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- Table of Contents
Facts about Potassium voltage-gated channel subfamily E member 3.
Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870). Associated with KCNC4/Kv3.
Human | |
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Gene Name: | KCNE3 |
Uniprot: | Q9Y6H6 |
Entrez: | 10008 |
Belongs to: |
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potassium channel KCNE family |
cardiac voltage-gated potassium channel accessory subunit; DKFZp781H21101; HOKPPMGC102685; HYPP; MGC129924; Minimum potassium ion channel-related peptide 2; MinK-related peptide 2; MiRP2; Potassium channel subunit beta MiRP2; potassium voltage-gated channel subfamily E member 3; potassium voltage-gated channel, Isk-related family, member 3; voltage-gated K+ channel subunit MIRP2
Mass (kDA):
11.71 kDA
Human | |
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Location: | 11q13.4 |
Sequence: | 11; NC_000011.10 (74454841..74467729, complement) |
Expressed in hippocampal neurons (at protein level) (PubMed:12954870). Widely expressed with highest levels in kidney and moderate levels in small intestine.
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Perikaryon. Cell projection, dendrite. Membrane raft. Colocalizes with KCNB1 at high-density somatodendritic clusters on the surface of hippocampal neurons.
PMID: 11104781 by Melman Y.F., et al. Structural determinants of KvLQT1 control by the KCNE family of proteins.
PMID: 10646604 by Schroeder B.C., et al. A constitutively open potassium channel formed by KCNQ1 and KCNE3.