KCNC3 Antibodies

AND KCNC3 ELISA kits, KCNC3 Proteins

Many biological assays use antibodies to detect KCNC3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KCNC3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KCNC3 antibodies...

We validate the specificity of these antibodies to KCNC3 by testing them on tissues known to express KCNC3 positively and negatively. Browse below to find the KCNC3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KCNC3 Infographic by Boster Bio

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KCNC3 (NM_004977) Human Over-expression Lysate

Human

$960
Cat # LS003748
100 µg

KCNC3 Overview

Facts about Potassium voltage-gated channel subfamily C member 3.

KCNC3 3D structure. Source: alphafold

Potassium voltage-gated channel subfamily C member 3 (KCNC3)

Voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient.

The channel displays rapid activation and inactivation kinetics (PubMed:10712820, PubMed:26997484, PubMed:22289912, PubMed:23734863, PubMed:16501573, PubMed:19953606, PubMed:21479265, PubMed:25756792). It plays a role in the regulation of the frequency, form and duration of action potentials in Purkinje cells.

Gene Information

Human
Gene Name:	KCNC3
Uniprot:	Q14003
Entrez:	3748

Family

Belongs to:

potassium channel family

Alternative Names

KSHIIID; KV3.3; potassium voltage-gated channel subfamily C member 3; potassium voltage-gated channel, Shaw-related subfamily, member 3; SCA13; Shaw-related voltage-gated potassium channel protein 3; spinocerebellar ataxia 13; voltage-gated potassium channel protein KV3.3; Voltage-gated potassium channel subunit Kv3.3

Molecular Weight

Mass (kDA):
80.578 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (50311937..50333536, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, presynaptic cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, axon. Cell projection, dendrite. Cell projection, dendritic spine membrane; Multi-pass membrane protein. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. In Detected on Purkinje cell dendritic spines, positioned perisynaptically but also in extrasynaptic positions along the spine membranes (By similarity). Detected at presynaptic calices of Held (By similarity). Colocalizes with the cortical actin cytoskeleton and the Arp2/3 complex (PubMed:26