KATNA1 Antibodies

AND KATNA1 ELISA kits, KATNA1 Proteins

Many biological assays use antibodies to detect KATNA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KATNA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KATNA1 antibodies...

We validate the specificity of these antibodies to KATNA1 by testing them on tissues known to express KATNA1 positively and negatively. Browse below to find the KATNA1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KATNA1 Infographic by Boster Bio

All KATNA1 Products

Product

Figures

Specificity

Applications

Price

Anti-p60 katanin Rabbit Monoclonal Antibody

Human

IF, ICC, WB

$370
Cat # M09752
100 μl/vial

KATNA1 (NM_007044) Human Over-expression Lysate

Human

$960
Cat # LS011104
100 µg

KATNA1 Overview

Facts about Katanin p60 ATPase-containing subunit A1.

KATNA1 3D structure. Source: alphafold

Katanin p60 ATPase-containing subunit A1 (KATNA1)

Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays as well as the launch of microtubules from the centrosome following nucleation.

Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, resulting in poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons might be required for their transportation to neuronal processes by microtubule-dependent motor proteins.

Gene Information

Human
Gene Name:	KATNA1
Uniprot:	O75449
Entrez:	11104

Family

Belongs to:

AAA ATPase family

Alternative Names

EC 3.6.4.3; katanin p60 (ATPase containing) subunit A 1; katanin p60 (ATPase-containing) subunit A 1; katanin p60 ATPase-containing subunit A1; Katanin p60 subunit A1; Katanin p60; KATNA1; p60 katanin

Molecular Weight

Mass (kDA):
55.965 kDA

Genomic Context


Human

Location:	6q25.1
Sequence:	6; NC_000006.12 (149594873..149649018, complement)

Subcellular Localizations

Cytoplasm. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Predominantly cytoplasmic (PubMed:9658175). Localized diffusely in the cytoplasm during the interphase (PubMed:10751153). During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase and telophase is localized at the midbody region (PubMed:19261606). Also localized to the interphase centrosome and the mitotic spindle poles (By similarity). Enhanced recruitment to the mitotic spindle pol

Interacting Proteins

KATNB1
KATNBL1

PTMs

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KATNA1

References

PMID: 9658175 by McNally F.J., et al. Katanin is responsible for the M-phase microtubule-severing activity in Xenopus eggs.

PMID: 10751153 by McNally K.P., et al. Two domains of p80 katanin regulate microtubule severing and spindle pole targeting by p60 katanin.