IVNS1ABP Antibodies

AND IVNS1ABP ELISA kits, IVNS1ABP Proteins

Many biological assays use antibodies to detect IVNS1ABP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IVNS1ABP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IVNS1ABP antibodies...

We validate the specificity of these antibodies to IVNS1ABP by testing them on tissues known to express IVNS1ABP positively and negatively. Browse below to find the IVNS1ABP antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IVNS1ABP Infographic by Boster Bio

All IVNS1ABP Products

Product

Figures

Specificity

Applications

Price

Influenza Virus NS1A Binding Protein (IVNS1ABP) (NM_006469) Human Recombinant Protein

$1249
Cat # PROTQ9Y6Y0
20 µg

Influenza Virus NS1A Binding Protein (IVNS1ABP) (NM_006469) Human Over-expression Lysate

Human

$628
Cat # LS010625
100 µg

IVNS1ABP Overview

Facts about Influenza virus NS1A-binding protein.

IVNS1ABP 3D structure. Source: alphafold

Influenza virus NS1A-binding protein (IVNS1ABP)

Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity).

Protects cells from cell death induced by actin destabilization (By similarity). Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway raising the concentration of AHR accessible to activate transcription (PubMed:16582008).

Gene Information

Human
Gene Name:	IVNS1ABP
Uniprot:	Q9Y6Y0
Entrez:	10625

Family

Belongs to:

No superfamily

Alternative Names

ARA3; aryl hydrocarbon receptor-associated 3; Aryl hydrocarbon receptor-associated protein 3; DKFZp686K06216; FLARA3; FLJ10962; FLJ35593; FLJ36593; HSPC068; influenza virus NS1A binding protein; influenza virus NS1A-binding protein; KIAA0850FLJ10069; KLHL39; NCX downstream gene 1; ND1; NS1; NS-1; NS1-binding protein; NS1BP; NS1-BPFLJ10411

Molecular Weight

Mass (kDA):
71.729 kDA

Genomic Context


Human

Location:	1q25.3
Sequence:	1; NC_000001.11 (185292367..185317292, complement)

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton. Nucleus, nucleoplasm. Associated with actin filaments (By similarity). Localization related to speckle domains which correspond to interchromatin granules and are enriched in factors involved in pre-mRNA splicing (PubMed:9696811). Following influenza A virus infection, redistribution from speckles to a more diffuse distribution in the nucleoplasm (PubMed:9696811).

Diseases

Influenza
Orthomyxoviridae Infections
Infective Disorder
Virus Diseases
Multiple Myeloma
Inflammation
Allergy
Chimera Disorder

Respiration Disorders
Cytogenetic Abnormality

Pathways

Cell Proliferation
Cellular Localization
Localization
Conjugation

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IVNS1ABP

References

PMID: 9696811 by Wolff T., et al. NS1-Binding protein (NS1-BP): a novel human protein that interacts with the influenza A virus nonstructural NS1 protein is relocalized in the nuclei of infected cells.

PMID: 16582008 by Dunham E.E., et al. The aryl hydrocarbon receptor signaling pathway is modified through interactions with a Kelch protein.