Irx2 Antibodies

AND Irx2 ELISA kits, Irx2 Proteins

Many biological assays use antibodies to detect Irx2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Irx2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Irx2 antibodies...

We validate the specificity of these antibodies to Irx2 by testing them on tissues known to express Irx2 positively and negatively. Browse below to find the Irx2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Irx2 Infographic by Boster Bio

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Anti-IRX2 Antibody

7 Q&As

Human

IF, IHC, WB

$360
Cat # A12205
100 µl

Irx2 Overview

Facts about Iroquois-class homeodomain protein IRX-2.

Iroquois-class homeodomain protein IRX-2 (Irx2)

Gene Information

Mouse
Gene Name:	Irx2
Uniprot:	P81066
Entrez:	16372

Family

Belongs to:

TALE/IRO homeobox family

Alternative Names

Homeodomain protein IRXA2; iroquois homeobox 2; Iroquois homeobox protein 2; iroquois-class homeodomain protein IRX-2; IRXA2

Molecular Weight

Mass (kDA):
49.484 kDA

Genomic Context


Mouse

Location:	13 C1\|13 39.23 cM
Sequence:	13;

Tissue Specificity

Expressed in specific and overlapping patterns with Irx1 and Irx3 in the developing and adult metanephric kidney. In the adult metanephros, renal expression is found in the loop of Henle in the S3 proximal tubule segment and in the thick ascending limb (TAL) of the distal tubule.

Diseases

Neoplasms
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Breast
Carcinoma
Nervousness
Mammary Neoplasms
Stomach Neoplasms
Tumor Progression
Cardiac Hypertrophy
Acquired Kyphosis
Malignant Neoplasm Of Lung

Sarcoma
Carcinogenesis
Digeorge Syndrome
Tumor Angiogenesis
Peripheral Nerve Sheath Neoplasm
Scoliosis, Unspecified
Nerve Sheath Tumors

Pathways

Regionalization
Neurogenesis
Dna Methylation
Methylation
Heart Development
Cell Migration
Dna Hypermethylation
Lung Development
Cell Fate Commitment
Localization
Limb Development
Cerebellum Formation

Cell Cycle
Hindbrain Development
Cell Differentiation
Angiogenesis
Pathogenesis
Excretion

PTMs

Methylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Irx2

References

PMID: 10926765 by Christoffels V.M., et al. Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart.

PMID: 10704856 by Cohen D.R., et al. Expression of two novel mouse Iroquois-class homeobox genes during neurogenesis.