Inpp5k Antibodies

AND Inpp5k ELISA kits, Inpp5k Proteins

Many biological assays use antibodies to detect Inpp5k, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Inpp5k in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Inpp5k antibodies...

We validate the specificity of these antibodies to Inpp5k by testing them on tissues known to express Inpp5k positively and negatively. Browse below to find the Inpp5k antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Inpp5k Infographic by Boster Bio

All Inpp5k Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-INPP5K Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A11107
100ul

SKIP (INPP5K) (NM_016532) Human Recombinant Protein

$1062
Cat # PROTQ9BT40
20 µg

SKIP (INPP5K) (NM_016532) Human Over-expression Lysate

Human

$628
Cat # LS051763
100 µg

Inpp5k Overview

Facts about Inositol polyphosphate 5-phosphatase K.

Inositol polyphosphate 5-phosphatase K (Inpp5k)

Inositol 5-phosphatase which functions on inositol 1,4,5- trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate compared to inositol 1,4,5- trisphosphate (By similarity).

Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; consequently, is the specific regulator for insulin signaling in skeletal muscle (PubMed:22247557, PubMed:22751929).

Gene Information

Mouse
Gene Name:	Inpp5k
Uniprot:	Q8C5L6
Entrez:	19062

Family

Belongs to:

inositol 1,4,5-trisphosphate 5-phosphatase type II family

Alternative Names

EC 3.1.3; EC 3.1.3.56; inositol polyphosphate-5-phosphatase K; PPS; skeletal muscle and kidney enriched inositol phosphatase; Skeletal muscle and kidney-enriched inositol phosphatase; SKIPinositol polyphosphate 5-phosphatase K

Molecular Weight

Mass (kDA):
54.159 kDA

Genomic Context


Mouse

Location:	11 B5\|11 45.92 cM
Sequence:	11;

Tissue Specificity

Expressed in the skeletal muscle and the eye.

Pathways

Transport
Water Transport
Localization
Excretion

Research Areas

Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Inpp5k

References

PMID: 9182797 by Hamilton B.A., et al. The vibrator mutation causes neurodegeneration via reduced expression of PITP alpha: positional complementation cloning and extragenic suppression.

PMID: 22247557 by Ijuin T., et al. Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).