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- Table of Contents
57 Citations 12 Q&As
71 Citations 10 Q&As
3 Citations 17 Q&As
Facts about Interleukin-17A.
Ligand for IL17RA and IL17RC (PubMed:17911633).
The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971).Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080). .
Human | |
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Gene Name: | IL17A |
Uniprot: | Q16552 |
Entrez: | 3605 |
Belongs to: |
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IL-17 family |
CTLA8; CTLA-8; CTLA8cytotoxic T-lymphocyte-associated serine esterase 8; Cytotoxic T-lymphocyte-associated antigen 8; IL17; IL-17; IL17A; IL-17A; IL-17Acytotoxic T-lymphocyte-associated protein 8; IL-17CTLA-8; IL17interleukin-17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A
Mass (kDA):
17.504 kDA
Human | |
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Location: | 6p12.2 |
Sequence: | 6; NC_000006.12 (52186375..52190638) |
Restricted to activated memory T-cells.
Secreted.
PMID: 8676080 by Fossiez F., et al. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.
PMID: 7499828 by Yao Z., et al. Human IL-17: a novel cytokine derived from T cells.
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page