Zinc finger protein Eos Antibodies

AND Ikzf4 ELISA kits, Zinc finger protein Eos Proteins

Many biological assays use antibodies to detect Zinc finger protein Eos, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein Eos in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein Eos antibodies...

We validate the specificity of these antibodies to Zinc finger protein Eos by testing them on tissues known to express Ikzf4 positively and negatively. Browse below to find the Ikzf4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ikzf4 Infographic by Boster Bio

All Ikzf4 Products

Product

Figures

Specificity

Applications

Price

Anti-Eos IKZF4 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A09383
100ul

ZNFN1A4 (IKZF4) (NM_022465) Human Over-expression Lysate

Human

$960
Cat # LS064375
100 µg

Ikzf4 Overview

Facts about Zinc finger protein Eos.

Zinc finger protein Eos (Ikzf4)

DNA-binding protein which binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2.

May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg).

Gene Information

Mouse
Gene Name:	Ikzf4
Uniprot:	Q8C208
Entrez:	22781

Family

Belongs to:

Ikaros C2H2-type zinc-finger protein family

Alternative Names

EOS; IKAROS family zinc finger 4 (Eos); Ikaros family zinc finger protein 4; KIAA1782Eos; zinc finger protein, subfamily 1A, 4 (Eos); zinc finger transcription factor Eos; ZNFN1A4zinc finger protein Eos

Molecular Weight

Mass (kDA):
64.155 kDA

Genomic Context


Mouse

Location:	10\|10 D3
Sequence:	10;

Tissue Specificity

Expressed mainly in the brain. Up-regulated in long term cultured astrocytes. Down-regulated during osteoclast differentiation.

Diseases

Autoimmune Diseases
Autoimmune Reaction
Autoimmunity
Alopecia Areata
Melanoma
Acute Lymphocytic Leukemia
Diabetes Mellitus
Eye Abnormalities
Horse Diseases
Malignant Neoplasms
Cytomegalovirus Infections
Leukemia

Diabetes Mellitus, Insulin-dependent
Allergy
L1 Acute Lymphoblastic Leukemia
Precursor B-cell Lymphoblastic Leukemia-lymphoma
Generalized Vitiligo
Dysequilibrium Syndrome

Pathways

Immune Response
Hypersensitivity
Pathogenesis

PTMs

Acetylation
Isopeptide bond

Phosphoprotein
Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ikzf4

References

PMID: 10218586 by Honma Y., et al. Eos: a novel member of the Ikaros gene family expressed predominantly in the developing nervous system.

PMID: 12444977 by Perdomo J., et al. The Ikaros family protein Eos associates with C-terminal-binding protein corepressors.