This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Influenza virus NS1A-binding protein.
Protects cells from cell death induced by actin destabilization (By similarity). Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway raising the concentration of AHR accessible to activate transcription (PubMed:16582008).
Human | |
---|---|
Gene Name: | IVNS1ABP |
Uniprot: | Q9Y6Y0 |
Entrez: | 10625 |
Belongs to: |
---|
No superfamily |
ARA3; aryl hydrocarbon receptor-associated 3; Aryl hydrocarbon receptor-associated protein 3; DKFZp686K06216; FLARA3; FLJ10962; FLJ35593; FLJ36593; HSPC068; influenza virus NS1A binding protein; influenza virus NS1A-binding protein; KIAA0850FLJ10069; KLHL39; NCX downstream gene 1; ND1; NS1; NS-1; NS1-binding protein; NS1BP; NS1-BPFLJ10411
Mass (kDA):
71.729 kDA
Human | |
---|---|
Location: | 1q25.3 |
Sequence: | 1; NC_000001.11 (185292367..185317292, complement) |
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus, nucleoplasm. Associated with actin filaments (By similarity). Localization related to speckle domains which correspond to interchromatin granules and are enriched in factors involved in pre-mRNA splicing (PubMed:9696811). Following influenza A virus infection, redistribution from speckles to a more diffuse distribution in the nucleoplasm (PubMed:9696811).
PMID: 9696811 by Wolff T., et al. NS1-Binding protein (NS1-BP): a novel human protein that interacts with the influenza A virus nonstructural NS1 protein is relocalized in the nuclei of infected cells.
PMID: 16582008 by Dunham E.E., et al. The aryl hydrocarbon receptor signaling pathway is modified through interactions with a Kelch protein.