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Integrin beta-2 Antibodies
AND ITGB2 ELISA kits, Integrin beta-2 Proteins
Many biological assays use antibodies to detect Integrin beta-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin beta-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin beta-2 antibodies...
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ITGB2 Infographic by Boster Bio
All ITGB2 Products
Product
Figures
Specificity
Applications
Price
Human
IHC, WB
$370
Cat # M00458-1
100 μg/vial
Cat # M00458-1
100 μg/vial
Human
Flow Cytometry
$515
Cat # M00458-Dyl550
100 μg/vial
Cat # M00458-Dyl550
100 μg/vial
Human
Flow Cytometry, IP, IHC-P, IHC-F, WB
$299
Cat # M00458-2
0.1 mg
Cat # M00458-2
0.1 mg
Mouse
Flow Cytometry, IP, IHC-P, IHC-F, WB
$299
Cat # M00458-3
0.1 mg
Cat # M00458-3
0.1 mg
ITGB2 Overview
Facts about Integrin beta-2.
Integrin beta-2 (ITGB2)
Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4.
Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen.Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain.
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGB2 |
| Uniprot: | P05107 |
| Entrez: | 3689 |
Family
| Belongs to: |
|---|
| integrin beta chain family |
Alternative Names
959 beta subunit precursor)10; CD18 antigen; CD18; CD18beta 2; cell surface adhesion glycoprotein (LFA-1; CR3; Integrin beta 2; integrin beta-2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1;macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; LFA-1 beta; LFA-1; MAC-1 beta; MF17; MFI7; P150; p150,95 beta
Molecular Weight
Mass (kDA):
84.782 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 21q22.3 |
| Sequence: | 21; NC_000021.9 (44885949..44928815, complement) |
Tissue Specificity
Leukocytes (PubMed:23775590). Expressed in neutrophils (at protein level) (PubMed:21193407, PubMed:28807980).
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Membrane raft; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Leukocyte Adhesion Deficiency
- Leukocyte-adhesion Deficiency Syndrome
- Malignant Neoplasms
- Neoplasms
- Dog Diseases
- Inflammation
- Immunologic Deficiency Syndromes
- Infective Disorder
- Carcinogenesis
- Ulcer
- Atherosclerosis
- Diabetes Mellitus
Interacting Proteins
- ABL1
- ITGAX
- NOTCH2NL
- RDX
- TLN2
Pathways
- Immune Response
- Cell Adhesion
- Wound Healing
- Cell Proliferation
- Pathogenesis
- Inflammatory Response
- Localization
- Secretion
- Cell Activation
- Fertilization
- Hepatocyte Proliferation
- Platelet Aggregation
- Menstruation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGB2
bosterbio.com/bosterbio-gene-info-cards/ITGB2
References
PMID: 3028646 by Kishimoto T.K., et al. Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family.
PMID: 1683838 by Weitzman J.B., et al. The gene organisation of the human beta 2 integrin subunit (CD18).
1 Publications of Boster Integrin beta-2 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.bbrc.2016.10.049, Identification of THY1 as a novel thyrotrope marker and THY1 antibody-mediated t...
*More publications can be found for each product on its corresponding product page