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Integrin alpha-M Antibodies
AND ITGAM ELISA kits, Integrin alpha-M Proteins
Many biological assays use antibodies to detect Integrin alpha-M, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-M in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-M antibodies...
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ITGAM Infographic by Boster Bio
All ITGAM Products
Product
Figures
Specificity
Applications
Price
Anti-CD11b/ITGAM Antibody Picoband®
7 Citations 4 Q&As
Human, Mouse, Rat
WB
$370
Cat # PA1943-1
100 μg/vial
Cat # PA1943-1
100 μg/vial
Anti-CD11b/ITGAM Antibody Picoband®
11 Citations 17 Q&As
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # PB9140
100 μg/vial
Cat # PB9140
100 μg/vial
Human
Flow Cytometry
$303
Cat # FC00144-APC
100 tests, 200 tests
Cat # FC00144-APC
100 tests, 200 tests
Human
Flow Cytometry
$299
Cat # FC00144-PE
100 tests, 200 tests
Cat # FC00144-PE
100 tests, 200 tests
Human
Flow Cytometry
$227
Cat # FC00144-FITC
100 tests, 200 tests
Cat # FC00144-FITC
100 tests, 200 tests
Anti-human CD11b Itgam Monoclonal Antibody Unconjugated, Flow Validated
1 Citations 3 Q&As
Human
Flow Cytometry
$143
Cat # FC00144
100ug, 500ug
Cat # FC00144
100ug, 500ug
Human
Flow Cytometry
$338
Cat # FC00144-PerCP
100 tests, 200 tests
Cat # FC00144-PerCP
100 tests, 200 tests
Human
Flow Cytometry
$360
Cat # FC00144-PerCP-Cy5.5
100 tests, 200 tests
Cat # FC00144-PerCP-Cy5.5
100 tests, 200 tests
Anti-CD11b ITGAM Rabbit Monoclonal Antibody
1 Citations 16 Q&As
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00144-1
100 μl
Cat # M00144-1
100 μl
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00144
100 μl
Cat # M00144
100 μl
Anti-CD11b/ITGAM Antibody Picoband®
5 Citations 16 Q&As
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00144-1
100 μg/vial
Cat # A00144-1
100 μg/vial
Human
Flow Cytometry
$303
Cat # FC00144-iFluor647
100 tests, 200 tests
Cat # FC00144-iFluor647
100 tests, 200 tests
Human
Flow Cytometry
$303
Cat # FC00144-mFluor450
100 tests, 200 tests
Cat # FC00144-mFluor450
100 tests, 200 tests
Human
Flow Cytometry
$515
Cat # A00144-Dyl488
100 μg/vial
Cat # A00144-Dyl488
100 μg/vial
Human
Flow Cytometry
$515
Cat # A00144-Dyl550
100 μg/vial
Cat # A00144-Dyl550
100 μg/vial
Human
IHC, WB
$431
Cat # M00144-2
100uL
Cat # M00144-2
100uL
ITGAM Overview
Facts about Integrin alpha-M.
Integrin alpha-M (ITGAM)
It's identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b.
Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGAM |
| Uniprot: | P11215 |
| Entrez: | 3684 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
antigen CD11b (p170); CD11 antigen-like family member B; CD11b antigen; CD11b; Cell surface glycoprotein MAC-1 subunit alpha; Complement component 3 receptor 3 subunit; CR-3 alpha chain; CR3A; CR3AMGC117044; Integrin alpha M; integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; MAC 1; MAC1; MAC-1; Mac1, alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha polypeptide; Mo1, alpha subunit; MO1A; neutrophil adherence receptor alpha-M subunit; Neutrophil adherence receptor; SLEB6
Molecular Weight
Mass (kDA):
127.179 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p11.2 |
| Sequence: | 16; NC_000016.10 (31259975..31332877) |
Tissue Specificity
Predominantly expressed in monocytes and granulocytes (PubMed:1346576). Expressed in neutrophils (at protein level) (PubMed:21193407).
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Membrane raft; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Inflammation
- Lupus Erythematosus, Systemic
- Leukemia
- Neoplasms
- Malignant Neoplasms
- Atherosclerosis
- Inflammatory Response
- Autoimmune Reaction
- Autoimmune Diseases
- Arthritis
- Acute Promyelocytic Leukemia
- Leukemia, Myelocytic, Acute
Pathways
- Pathogenesis
- Inflammatory Response
- Cell Adhesion
- Neutrophil Activation
- Immune Response
- Chemotaxis
- Monocyte Activation
- Cell Differentiation
- Phagocytosis
- Secretion
- Cell Cycle
- Platelet Activation
- Leukocyte Activation
PTMs
- Phosphorylation
- Cleavage
- Reduction
- Oxidation
Research Areas
- Breast Cancer
- Cancer
- Cell Biology
- Cellular Markers
- Glia Markers
- Hematopoietic Stem Cell Markers
- Immunology
- Innate Immunity
- Microglia Markers
- Myeloid Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGAM
bosterbio.com/bosterbio-gene-info-cards/ITGAM
References
PMID: 2457584 by Corbi A.L., et al. The human leukocyte adhesion glycoprotein Mac-1 (complement receptor type 3, CD11b) alpha subunit. Cloning, primary structure, and relation to the integrins, von Willebrand factor and factor B.
PMID: 2833753 by Arnaout M.A., et al. Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrins.
12 Publications of Boster Integrin alpha-M Antibodies & ELISA Kits
- PubMed ID: PMID:25691929, Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial...
- PubMed ID: 10.1159/000358235, The Neurovascular Protective Effects of Huperzine A on D-Galactose-Induced Infla...
- PubMed ID: 10.1016/j.cellbi.2009.01.008, Rat bone marrow derived mesenchymal progenitor cells support mouse ES cell growt...
- PubMed ID: 10.1007/s12192-010-0203-0, Anti-heat shock protein 70 autoantibody epitope changes and BD091 promotes ather...
- PubMed ID: 28100749, Promoted interaction of C/EBP%u03B1 with demethylated Cxcr3 gene promoter contri...
- PubMed ID: 20607472, Anti-heat shock protein 70 autoantibody epitope changes and BD091 promotes ather...
- PubMed ID: 20582224, Cloning, characterization, and expression analysis of goat (Capra hircus) phosph...
- PubMed ID: 2892295, Cloning, characterization, and expression analysis of goat (Capra hircus) phosph...
- PubMed ID: 25491263, Ren B, Zhang Yx, Zhou Hx, Sun Fw, Zhang Zf, Wei Z, Zhang Cy, Si Dw. J Neurol Sci...
- PubMed ID: 23158928, Zhao G, Wang S, Wang Z, Sun A, Yang X, Qiu Z, Wu C, Zhang W, Li H, Zhang Y, Zhao...
- PubMed ID: 25691929, Mu L, Jing C, Guo Z. Iran J Basic Med Sci. 2014 Nov;17(11):874-8. Expressions Of...
- PubMed ID: 22142175, Yuan Y, Su Z, Pu Y, Liu X, Chen J, Zhu F, Zhu Y, Zhang H, He C. Br J Pharmacol. ...
*More publications can be found for each product on its corresponding product page