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Integrin alpha-L Antibodies
AND ITGAL ELISA kits, Integrin alpha-L Proteins
Many biological assays use antibodies to detect Integrin alpha-L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-L antibodies...
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ITGAL Infographic by Boster Bio
All ITGAL Products
Product
Figures
Specificity
Applications
Price
Anti-CD11a/ITGAL Antibody Picoband®
2 Citations 1 Q&As
Human
Flow Cytometry, IHC, ICC, WB
$370
Cat # A04466-1
100 μg/vial
Cat # A04466-1
100 μg/vial
Human
Flow Cytometry, IF, Functional Assay
$486
Cat # M04466
100ug/vial
Cat # M04466
100ug/vial
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M04466-1
100 μl
Cat # M04466-1
100 μl
Human
Flow Cytometry
$147
Cat # FC04466
100ug, 500ug
Cat # FC04466
100ug, 500ug
Human
Flow Cytometry
$231
Cat # FC04466-FITC
100 tests, 200 tests
Cat # FC04466-FITC
100 tests, 200 tests
Mouse
Flow Cytometry, IP, IHC-F
$299
Cat # M04466-2
0.1 mg
Cat # M04466-2
0.1 mg
Human
ELISA, Flow Cytometry, FTA
$349
Cat # M04466-4
100 μg
Cat # M04466-4
100 μg
ITGAL Overview
Facts about Integrin alpha-L.
Integrin alpha-L (ITGAL)
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4.
Integrin alpha-L/beta-2 is also a receptor for F11R (PubMed:11812992, PubMed:15528364).Involved in many different immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity (PubMed:15356110).
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGAL |
| Uniprot: | P20701 |
| Entrez: | 3683 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
CD11 antigen-like family member A; CD11a antigen; CD11a; CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide; Integrin alpha L; integrin alpha-L; integrin gene promoter; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; Leukocyte function-associated molecule 1 alpha chain; LFA-1 alpha; LFA-1; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte function-associated antigen 1
Molecular Weight
Mass (kDA):
128.77 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p11.2 |
| Sequence: | 16; NC_000016.10 (30472683..30523185) |
Tissue Specificity
Leukocytes.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Lupus Erythematosus, Systemic
- Malignant Neoplasms
- Inflammation
- Autoimmune Reaction
- Neoplasms
- Inflammatory Bowel Diseases
- Intestinal Diseases
- Autoimmune Diseases
- Autoimmunity
- Sclerosis
- Atresia
- Hepatitis B
Interacting Proteins
- ICAM1
- PTPRC
Pathways
- Dna Methylation
- Methylation
- Pathogenesis
- Demethylation
- Dna Hypomethylation
- Cell Adhesion
- Immune Response
- Secretion
- Response To Stress
- Dna Hypermethylation
- Aging
PTMs
- Methylation
Research Areas
- Adaptive Immunity
- Cytokine Research
- Immunology
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGAL
bosterbio.com/bosterbio-gene-info-cards/ITGAL
References
PMID: 2537322 by Larson R.S., et al. Primary structure of the leukocyte function-associated molecule-1 alpha subunit: an integrin with an embedded domain defining a protein superfamily.
PMID: 8099450 by Shelley C.S., et al. Identification of cell-specific and developmentally regulated nuclear factors that direct myeloid and lymphoid expression of the CD11a gene.
2 Publications of Boster Integrin alpha-L Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.ejphar.2005.12.080, Protective effect of bicyclol on acute hepatic failure induced by lipopolysaccha...
- PubMed ID: 25691929, Mu L, Jing C, Guo Z. Iran J Basic Med Sci. 2014 Nov;17(11):874-8. Expressions Of...
*More publications can be found for each product on its corresponding product page