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Integrin alpha-5 Antibodies
AND ITGA5 ELISA kits, Integrin alpha-5 Proteins
Many biological assays use antibodies to detect Integrin alpha-5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-5 antibodies...
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ITGA5 Infographic by Boster Bio
All ITGA5 Products
Product
Figures
Specificity
Applications
Price
Anti-Integrin alpha 5/ITGA5 Antibody Picoband®
3 Citations 1 Q&As
Human, Mouse, Rat
WB
$370
Cat # PB9254
100 μg/vial
Cat # PB9254
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01911
100 μl
Cat # M01911
100 μl
Anti-Integrin alpha 5/ITGA5 Antibody Picoband®
5 Citations 8 Q&As
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A01911
100 μg/vial
Cat # A01911
100 μg/vial
Mouse
Flow Cytometry, IHC-F, ICC
$299
Cat # M01911-1
0.1 mg
Cat # M01911-1
0.1 mg
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A01911-1
100ul
Cat # A01911-1
100ul
Human
ELISA
$750
Cat # EK2227
96 wells/kit, with removable strips.
Cat # EK2227
96 wells/kit, with removable strips.
ITGA5 Overview
Facts about Integrin alpha-5.
Integrin alpha-5 (ITGA5)
Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands.
ITGA5:ITGB1 binds to PLA2G2A by means of a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and improved ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 functions as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881).
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGA5 |
| Uniprot: | P08648 |
| Entrez: | 3678 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
Integrin alpha 5 beta 1; VLA-5
Molecular Weight
Mass (kDA):
114.536 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.13 |
| Sequence: | 12; NC_000012.12 (54395261..54419266, complement) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. Cell surface.
Interacting Proteins
- ENG
- ITGB1
- NRP1
- Nrp1
- SHARPIN
PTMs
- Cleavage on pair of basic residues
- Disulfide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGA5
bosterbio.com/bosterbio-gene-info-cards/ITGA5
References
PMID: 2958481 by Argraves W.S., et al. Amino acid sequence of the human fibronectin receptor.
PMID: 1834647 by Birkenmeier T.M., et al. The alpha 5 beta 1 fibronectin receptor. Characterization of the alpha 5 gene promoter.
5 Publications of Boster Integrin alpha-5 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.ijcard.2013.01.239, Calreticulin overexpression correlates with integrin-α5 and transforming growth...
- PubMed ID: 26680220, Silencing of Paternally Expressed Gene 10 Inhibits Trophoblast Proliferation and...
- PubMed ID: 24643246, A Small Physiological Electric Field Mediated Responses of Extravillous Trophobl...
- PubMed ID: 19918321, Characterization of Rat Hair Follicle Stem Cells Selected by Vario Magnetic Acti...
- PubMed ID: 2775103, Characterization of Rat Hair Follicle Stem Cells Selected by Vario Magnetic Acti...
*More publications can be found for each product on its corresponding product page