ISG20 Antibodies

AND ISG20 ELISA kits, ISG20 Proteins

Many biological assays use antibodies to detect ISG20, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ISG20 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ISG20 antibodies...

We validate the specificity of these antibodies to ISG20 by testing them on tissues known to express ISG20 positively and negatively. Browse below to find the ISG20 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ISG20 Infographic by Boster Bio

All ISG20 Products

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Product

Figures

Specificity

Applications

Price

Anti-ISG20 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A06713
100ul

ISG20 (NM_002201) Human Over-expression Lysate

Human

$628
Cat # LS003669
100 µg

ISG20 Overview

Facts about Interferon-stimulated gene 20 kDa protein.

ISG20 3D structure. Source: alphafold

Interferon-stimulated gene 20 kDa protein (ISG20)

Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and has minor activity towards single- stranded DNA. Exhibits antiviral activity against RNA viruses such as hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) within an exonuclease-dependent manner.

May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis. .

Gene Information

Human
Gene Name:	ISG20
Uniprot:	Q96AZ6
Entrez:	3669

Family

Belongs to:

exonuclease superfamily

Alternative Names

CD25; Estrogen-regulated transcript 45 protein; HEM45EC 3.1.13.1; interferon stimulated exonuclease gene 20kDa; interferon stimulated gene (20kD); interferon-stimulated gene 20 kDa protein; Promyelocytic leukemia nuclear body-associated protein ISG20

Molecular Weight

Mass (kDA):
20.363 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (88635614..88656483)

Tissue Specificity

Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung. Up regulated by E2 in estrogen receptor-positive breast cancer lines.

Subcellular Localizations

Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body.

Diseases

Virus Diseases
Infective Disorder
Leukemia
Hepatitis
Malignant Neoplasms
Acute Promyelocytic Leukemia
Hepatitis C
Neoplasms
Hepatitis, Chronic
Endometrial Polyp
Cell Transformation, Neoplastic
Hepatitis B
Lupus Erythematosus, Systemic

Influenza
Dna Virus Infections
Autoimmune Diseases
Inflammation
Inflammatory Response
Innate Immune Response
Rna Virus Infections

Pathways

Immune Response
Localization
Pathogenesis
Inflammatory Response
Cell Cycle
Innate Immune Response
Oncogenesis
Rna Interference
Response To Lipopolysaccharide
Cell Migration
Gene Silencing
Adaptive Immune Response
Response To Virus

Virulence
Cell Division
Reverse Transcription
Viral Transcription
Translation
Cell Differentiation
Cell Proliferation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ISG20

References

PMID: 9235947 by Gongora C., et al. Molecular cloning of a new interferon-induced PML nuclear bodies- associated protein.

PMID: 9569007 by Pentecost B.T.; Expression and estrogen regulation of the HEM45 mRNA in human tumor lines and in the rat uterus.