This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
Ing4 Antibodies
AND Ing4 ELISA kits, Ing4 Proteins
Many biological assays use antibodies to detect Ing4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ing4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ing4 antibodies...
Previous: SEPTIN9
Next: Mrpl50
Ing4 Infographic by Boster Bio
All Ing4 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
WB
$399
Cat # A02664-1
100μl
Cat # A02664-1
100μl
Ing4 Overview
Facts about Inhibitor of growth protein 4.
Inhibitor of growth protein 4 (Ing4)
Component of the HBO1 complex that has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication.
May inhibit tumor development by regulating the transcriptional output of signaling pathways that regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Ing4 |
| Uniprot: | Q8C0D7 |
| Entrez: | 28019 |
Family
| Belongs to: |
|---|
| ING family |
Alternative Names
candidate tumor suppressor p33 ING1 homolog; inhibitor of growth family, member 4; inhibitor of growth protein 4; MGC12557; my036; p29ING4brain my036 protein
Molecular Weight
Mass (kDA):
28.528 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 6 F2|6 59.17 cM |
| Sequence: | 6; |
Tissue Specificity
Isoform 2, isoform 3, isoform 4 and isoform 5 are expressed in the mammary gland, ovary, spleen and muscle.
Diseases
- Neoplasms
- Malignant Neoplasms
- Tumor Angiogenesis
- Carcinoma
- Neoplasm Metastasis
- Pathologic Neovascularization
- Cell Transformation, Neoplastic
- Cell Invasion
- Malignant Neoplasm Of Breast
- Glioma
- Lung Neoplasms
- Adenocarcinoma
Pathways
- Angiogenesis
- Cell Cycle
- Cell Growth
- Cell Proliferation
- Localization
- Cell Migration
- Contact Inhibition
- Methylation
- Pathogenesis
- Cell Cycle Arrest
- Histone H4 Acetylation
- Dna Repair
- Dna Replication
PTMs
- Acetylation
- Methylation
- Cleavage
- Phosphorylation
Research Areas
- Chromatin Research
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ing4
bosterbio.com/bosterbio-gene-info-cards/Ing4
References
PMID: 11888890 by Ha S., et al. Mouse ING1 homologue, a protein interacting with A1, enhances cell death and is inhibited by A1 in mammary epithelial cells.