Inhibitor of growth protein 2 (ING2)

Seems to participate in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, likely by enhancing acetylation of p53/TP53. Part of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones.

ING2 activity appears to be modulated by binding to phosphoinositides (PtdInsPs). .