IMPA1 Antibodies

AND IMPA1 ELISA kits, IMPA1 Proteins

Many biological assays use antibodies to detect IMPA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IMPA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IMPA1 antibodies...

We validate the specificity of these antibodies to IMPA1 by testing them on tissues known to express IMPA1 positively and negatively. Browse below to find the IMPA1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IMPA1 Infographic by Boster Bio

All IMPA1 Products

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Product

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Specificity

Applications

Price

Anti-Inositol monophosphatase 1 IMPA1 Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A05882
100ul

IMPA1 (NM_005536) Human Recombinant Protein

$813
Cat # PROTP29218
20 µg

Anti-IMPA1 Antibody

Human

$299
Cat # M05882
50 µl

IMPA1 (NM_005536) Human Over-expression Lysate

Human

$628
Cat # LS003612
100 µg

IMPA1 Overview

Facts about Inositol monophosphatase 1.

IMPA1 3D structure. Source: alphafold

Inositol monophosphatase 1 (IMPA1)

Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and may use myo- inositol monophosphates, myo-inositol 1,3-diphosphate, myo- inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1- phosphate, beta-glycerophosphate, and 2'-AMP as substrates.

Gene Information

Human
Gene Name:	IMPA1
Uniprot:	P29218
Entrez:	3612

Family

Belongs to:

inositol monophosphatase superfamily

Alternative Names

EC 3.1.3.25; IMP 1; IMP; IMP1; IMPA; IMPA1; IMPase 1; inositol monophosphatase 1; inositol(myo)-1(or 4)-monophosphatase 1; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; MRT59; Myo-Inositol Monophosphatase 1

Molecular Weight

Mass (kDA):
30.189 kDA

Genomic Context


Human

Location:	8q21.13
Sequence:	8; NC_000008.11 (81656914..81686354, complement)

Subcellular Localizations

Cytoplasm.

Diseases

Bipolar Disorder
Sclerosis
Mood Disorders
Manic
Febrile Convulsions
Schizophrenia
Depressive Disorder
Classical Galactosemia
Primary Lateral Sclerosis
Neurodegenerative Disorders
Amyotrophic Lateral Sclerosis
Injury Of Central Nervous System

Dysequilibrium Syndrome
Neuroblastoma
Hypothyroidism
Cns Disorder
Nerve Degeneration
Multiple Sclerosis
Insulin Sensitivity

Interacting Proteins

IMPA2

Pathways

Transport
Protein Phosphorylation
Cell Migration
Endocytosis
Mrna Transport
Localization
Translation
Cell Growth
Exocytosis

Pachytene
Pathogenesis
Myo-inositol Transport
Autophagy

PTMs

Phosphorylation

Dephosphorylation

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IMPA1

References

PMID: 1377913 by McAllister G., et al. cDNA cloning of human and rat brain myo-inositol monophosphatase. Expression and characterization of the human recombinant enzyme.

PMID: 9339367 by Sjoeholt G., et al. Genomic structure and chromosomal localization of a human myo- inositol monophosphatase gene (IMPA).