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- Table of Contents
Facts about Interleukin-2 receptor subunit alpha.
Receptor for interleukin-2.
The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.TREGs suppress the activation and expansion of autoreactive T-cells. .
Human | |
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Gene Name: | IL2RA |
Uniprot: | P01589 |
Entrez: | 3559 |
Belongs to: |
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No superfamily |
CD25 antigen; CD25; IDDM10; IL-2 R alpha; IL-2 receptor subunit alpha; IL2R alpha; IL-2R subunit alpha; IL2R; IL2RA; IL-2Ra; IL-2-RA; IL2-RA; interleukin 2 receptor, alpha; interleukin-2 receptor subunit alpha; p55; TAC antigen; TCGFR
Mass (kDA):
30.819 kDA
Human | |
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Location: | 10p15.1 |
Sequence: | 10; NC_000010.11 (6010689..6062367, complement) |
Membrane; Single-pass type I membrane protein.
PMID: 6090949 by Nikaido T., et al. Molecular cloning of cDNA encoding human interleukin-2 receptor.
PMID: 6090948 by Leonard W.J., et al. Molecular cloning and expression of cDNAs for the human interleukin-2 receptor.
*More publications can be found for each product on its corresponding product page