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- Table of Contents
2 Citations 6 Q&As
Facts about Interleukin-17C.
Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy can be observed with TNF and IL1B in inducing DEFB2 from keratinocytes.
Human | |
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Gene Name: | IL17C |
Uniprot: | Q9P0M4 |
Entrez: | 27189 |
Belongs to: |
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IL-17 family |
CX2; Cytokine CX2; IL17C; IL-17C; IL-17CMGC126884; interleukin 17C; interleukin-17C; MGC138401
Mass (kDA):
21.765 kDA
Human | |
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Location: | 16q24.2 |
Sequence: | 16; NC_000016.10 (88638572..88640468) |
Secreted.
PMID: 10639155 by Li H., et al. Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family.
PMID: 21993849 by Song X., et al. IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens.
*More publications can be found for each product on its corresponding product page