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- Table of Contents
4 Citations 5 Q&As
2 Citations 10 Q&As
2 Citations 5 Q&As
Facts about Insulin-like growth factor-binding protein 3.
Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. .
Human | |
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Gene Name: | IGFBP3 |
Uniprot: | P17936 |
Entrez: | 3486 |
Belongs to: |
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No superfamily |
acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; growth hormone-dependent binding protein; IBP-3; IBP3BP-53; IGF-binding protein 3; IGFBP3; IGFBP-3; insulin-like growth factor binding protein 3; insulin-like growth factor-binding protein 3
Mass (kDA):
31.674 kDA
Human | |
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Location: | 7p12.3 |
Sequence: | 7; NC_000007.14 (45912245..45921272, complement) |
Expressed by most tissues. Present in plasma.
Secreted.
PMID: 2464130 by Wood W.I., et al. Cloning and expression of the growth hormone-dependent insulin-like growth factor-binding protein.
PMID: 1695633 by Cubbage M.L., et al. Insulin-like growth factor binding protein-3. Organization of the human chromosomal gene and demonstration of promoter activity.
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