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IGF1R Antibodies
AND IGF1R ELISA kits, IGF1R Proteins
Many biological assays use antibodies to detect IGF1R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGF1R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGF1R antibodies...
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IGF1R Infographic by Boster Bio
All IGF1R Products
Product
Figures
Specificity
Applications
Price
Human IGF1R/Igf1 Receptor ELISA Kit PicoKine®
1 Citations 9 Q&As
Human
ELISA
$499
Cat # EK0776
96 wells/kit, with removable strips.
Cat # EK0776
96 wells/kit, with removable strips.
Anti-IGF1 Receptor/IGF1R Antibody Picoband®
11 Citations 19 Q&As
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PA1746
100 μg/vial
Cat # PA1746
100 μg/vial
Anti-IGF1 Receptor/Igf1r Antibody Picoband®
6 Citations 4 Q&As
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A00070
100 μg/vial
Cat # A00070
100 μg/vial
Anti-IGF-1R (Ab-1161) Antibody
5 Citations 16 Q&As
Human, Mouse, Rat
IF, IHC, WB
$360
Cat # A00070-1
100 µl
Cat # A00070-1
100 µl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1291
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1291
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1966
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1966
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2433
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2433
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA, IP, IHC, WB
$380
Cat # A00070Y1161-1
100ul
Cat # A00070Y1161-1
100ul
Human, Monkey, Mouse, Rat
ELISA, WB
$380
Cat # A00070Y1165Y1166
100ul
Cat # A00070Y1165Y1166
100ul
Human, Mouse, Rat
Flow Cytometry, WB
$523
Cat # M00070-1
100 µl
Cat # M00070-1
100 µl
IGF1R Overview
Facts about Insulin-like growth factor 1 receptor.
Insulin-like growth factor 1 receptor (IGF1R)
Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity.
The activated IGF1R is involved in cell growth and survival management. IGF1R is crucial for tumor survival and transformation of malignant cell.
Gene Information
| Human | |
|---|---|
| Gene Name: | IGF1R |
| Uniprot: | P08069 |
| Entrez: | 3480 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
CD221 antigen; CD221; EC 2.7.10; EC 2.7.10.1; IGF1R; IGF-1R; IGF-I R; IGF-I receptor; IGFIR; IGF-IR; IGFR; insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; JTK13; MGC142170; MGC142172; MGC18216; soluble IGF1R variant 1; soluble IGF1R variant 2
Molecular Weight
Mass (kDA):
154.793 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q26.3 |
| Sequence: | 15; NC_000015.10 (98648539..98964530) |
Tissue Specificity
Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of the colon, pancreas prostate and kidney.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Neoplasm Metastasis
- Carcinoma
- Growth Retardation
- Malignant Paraganglionic Neoplasm
- Cell Transformation, Neoplastic
- Fetal Growth Retardation
- Dwarfism
- Diabetes Mellitus
Interacting Proteins
- ARHGEF12
- CAMP
- Crk
- CSK
- CTNNB1
- IGF1
- KCNIP3
- LEF1
- MDM2
- PIK3R1
Pathways
- Cell Proliferation
- Cell Growth
- Pathogenesis
- Aging
- Cell Cycle
- Cell Death
- Secretion
- Localization
- Gene Silencing
- Angiogenesis
- Cell Migration
- Rna Interference
- Methylation
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGF1R
bosterbio.com/bosterbio-gene-info-cards/IGF1R
References
PMID: 2877871 by Ullrich A., et al. Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.
PMID: 1316909 by Abbot A.M., et al. Insulin-like growth factor I receptor gene structure.
12 Publications of Boster IGF1R Antibodies & ELISA Kits
- PubMed ID: PMID:28386316, Energy intake correlates with the levels of fatty acid synthase and insulin-like...
- PubMed ID: -, Alashti, M.,Shirvani, H.,Sabzevari Rad,R. et al.Effects of different small-sided...
- PubMed ID: 22335030, Expression of IGF-1R, VEGF-C and D2-40 and their correlation with lymph node met...
- PubMed ID: 27340351, Long-pulse gastric electrical stimulation protects interstitial cells of Cajal i...
- PubMed ID: 22720981, Insulin-like growth factors in endometrioid adenocarcinoma: Correlation with cli...
- PubMed ID: 19424673, Treating Human Meniscal Fibrochondrocytes with hIGF-1 Gene by Liposome
- PubMed ID: 27833148, IGF-1/IGF-1R/hsa-let-7c axis regulates the committed differentiation of stem cel...
- PubMed ID: 27725848, Let-7a inhibits migration of melanoma cells via down-regulation of HMGA2 express...
- PubMed ID: 29650947, Liu GX, Ma S, Li Y, Yu Y, Zhou YX, Lu YD, Jin L, Wang ZL, Yu JH. Exp Mol Med. 20...
- PubMed ID: 28290552, Lai J, Chen F, Chen J, Ruan G, He M, Chen C, Tang J, Wang DW. Sci Rep. 2017 Mar ...
- PubMed ID: 28669683, Zhang, Y., Zhang, L., Yu, C.F., Du, X.Y., Liu, X.R., Liu, J.Z.,…, & Cao, B.Y. ...
- PubMed ID: 28386316, Ramdhave AS, Ojha S, Nandave M. Am J Transl Res. 2017 Mar 15;9(3):830-844. eColl...
*More publications can be found for each product on its corresponding product page