IGBP1 Antibodies

AND IGBP1 ELISA kits, IGBP1 Proteins

Many biological assays use antibodies to detect IGBP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IGBP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IGBP1 antibodies...

We validate the specificity of these antibodies to IGBP1 by testing them on tissues known to express IGBP1 positively and negatively. Browse below to find the IGBP1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IGBP1 Infographic by Boster Bio

All IGBP1 Products

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Product

Figures

Specificity

Applications

Price

Anti-IGBP1 Mouse Monoclonal Antibody [Clone ID: OTI4F6]

Human

Flow Cytometry, IF, WB

$523
Cat # M05930
100 µl

Anti-IGBP1 Antibody Picoband®

Human

ELISA, Flow Cytometry, WB

$370
Cat # A05930-2
100 μg/vial

IGBP1 (NM_001551) Human Over-expression Lysate

Human

$628
Cat # LS003476
100 µg

IGBP1 Overview

Facts about Immunoglobulin-binding protein 1.

IGBP1 3D structure. Source: alphafold

Immunoglobulin-binding protein 1 (IGBP1)

Associated to surface IgM-receptor; may be involved in signal transduction. Involved in regulation of the catalytic activity of the phosphatases PP2A, PP4 and PP6 by protecting their partly folded catalytic subunits from degradative polyubiquitination until they associate with regulatory subunits.

Gene Information

Human
Gene Name:	IGBP1
Uniprot:	P78318
Entrez:	3476

Family

Belongs to:

IGBP1/TAP42 family

Alternative Names

ALPHA-4; B cell signal transduction molecule alpha 4; bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ); B-cell signal transduction molecule alpha 4; CD79a-binding protein 1; IBP1; immunoglobulin (CD79A) binding protein 1; immunoglobulin-binding protein 1; Protein alpha-4; protein phosphatase 2A, regulatory subunit alpha-4; Renal carcinoma antigen NY-REN-16

Molecular Weight

Mass (kDA):
39.222 kDA

Genomic Context


Human

Location:	Xq13.1
Sequence:	X; NC_000023.11 (70133447..70166324)

Tissue Specificity

Ubiquitously expressed with highest levels in heart, skeletal muscle and pancreas.

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Lymphoma
Hyperplasia
Carcinoma
Multiple Myeloma
Adenocarcinoma
Cell Transformation, Neoplastic
Lung Neoplasms
Congenital Ocular Coloboma (disorder)
Stenosis
Neoplasms, Radiation-induced
Atresia

Thymus Neoplasms
Malignant Neoplasm Of Breast
Malignant Neoplasm Of Lung
Immunologic Deficiency Syndromes
Carcinoma In Situ
Acute Erythroblastic Leukemia
Vascular System Injuries

Interacting Proteins

HSPB1
MID1
PPP2CA
PPP2CB
PPP4C

PPP6C
TIPRL

Pathways

Cell Proliferation
Translation
Cell Growth
Localization
Cell Cycle
Regulation Of Phosphatase Activity
Cell Activation
Cell Migration
Dna Hypomethylation
Cell Development

Proteolysis
B Cell Activation
Reverse Transcription
Chemotaxis
Angiogenesis

PTMs

Phosphorylation
Dephosphorylation

Ubiquitination
Reduction

Research Areas

Protein Phosphatase
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IGBP1

References

PMID: 9441740 by Onda M., et al. Expression and chromosomal localization of the human alpha 4/IGBP1 gene, the structure of which is closely related to the yeast TAP42 protein of the rapamycin-sensitive signal transduction pathway.

PMID: 9647778 by Chen J., et al. Alpha 4 associates with protein phosphatases 2A, 4, and 6.