IDH3B Antibodies

AND IDH3B ELISA kits, IDH3B Proteins

Many biological assays use antibodies to detect IDH3B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IDH3B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IDH3B antibodies...

We validate the specificity of these antibodies to IDH3B by testing them on tissues known to express IDH3B positively and negatively. Browse below to find the IDH3B antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IDH3B Infographic by Boster Bio

All IDH3B Products

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Product

Figures

Specificity

Applications

Price

Anti-IDH3B Antibody

Human, Mouse, Rat

$405
Cat # A09433
100ul

Anti-IDH3B Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A09433-1
100ul

Anti-IDH3B Antibody (N-term)

Human

IHC-P, WB

$299
Cat # A09433-2
80 µl

Anti-IDH3B Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IP, IHC, WB

$370
Cat # A09433-3
100 μg/vial

IDH3B Overview

Facts about Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial.

IDH3B 3D structure. Source: alphafold

Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B)

Plays a structural role to facilitate the assembly and make sure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the complete activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the meeting and combined function of both heterodimers.

Gene Information

Human
Gene Name:	IDH3B
Uniprot:	O43837
Entrez:	3420

Family

Belongs to:

isocitrate and isopropylmalate dehydrogenases family

Alternative Names

EC 1.1.1; EC 1.1.1.41; FLJ11043; H-IDHB; isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; isocitrate dehydrogenase 3 (NAD+) beta; isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, beta subunit; Isocitric dehydrogenase subunit beta; MGC903; NAD(+)-specific ICDH subunit beta; NAD+-specific ICDH; NAD+-specific isocitrate dehydrogenase b subunit; NAD+-specific isocitrate dehydrogenase beta; RP46

Molecular Weight

Mass (kDA):
42.184 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (2658394..2664223, complement)

Subcellular Localizations

Mitochondrion.

Diseases

Retinitis Pigmentosa
Carcinoma
Neoplasms
Neoplasm Metastasis
Retinal Degeneration
Liver Carcinoma
Hepatitis
Nerve Degeneration
Malignant Neoplasm Of Liver
Lung Diseases
Malignant Neoplasm Of Lung

Cancer Of Nasopharynx
Lung Diseases, Obstructive
Chronic Obstructive Airway Disease
Malignant Neoplasms
Obesity
Liver Neoplasms

Pathways

Translation
Metabolic Process
Cell Cycle
Hydrogen Peroxide Metabolic Process
Protein Folding
Cellular Response To Reactive Oxygen Species
Response To Reactive Oxygen Species
Aging
Immune Response

Cell Redox Homeostasis
Regulation Of Mitochondrial Membrane Potential
Rna Splicing

PTMs

Oxidation

Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IDH3B

References

PMID: 10601238 by Kim Y.-O., et al. Identification and functional characterization of a novel, tissue- specific NAD+-dependent isocitrate dehydrogenase beta subunit isoform.

PMID: 28098230 by Ma T., et al. Molecular mechanism of the allosteric regulation of the alphagamma heterodimer of human NAD-dependent isocitrate dehydrogenase.