Bone sialoprotein 2 Antibodies

AND IBSP ELISA kits, Bone sialoprotein 2 Proteins

Many biological assays use antibodies to detect Bone sialoprotein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Bone sialoprotein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Bone sialoprotein 2 antibodies...

We validate the specificity of these antibodies to Bone sialoprotein 2 by testing them on tissues known to express IBSP positively and negatively. Browse below to find the IBSP antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IBSP Infographic by Boster Bio

All IBSP Products

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Product

Figures

Specificity

Applications

Price

Anti-Bone Sialoprotein/IBSP Antibody Picoband®

3 Citations

Human, Mouse, Rat

IHC, WB

$370
Cat # PA1505
100 μg/vial

Anti-Bone Sialoprotein/IBSP Antibody Picoband®

2 Citations 7 Q&As

Mouse, Rat

IHC, WB

$370
Cat # PA1887
100 μg/vial

Anti-IBSP Antibody Picoband®

3 Citations

Human, Mouse, Rat

$370
Cat # A03183
100 μg/vial

Bone Sialoprotein (IBSP) (NM_004967) Human Over-expression Lysate

Human

$628
Cat # LS003381
100 µg

IBSP Overview

Facts about Bone sialoprotein 2.

IBSP 3D structure. Source: alphafold

Bone sialoprotein 2 (IBSP)

Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix.

Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.

Gene Information

Human
Gene Name:	IBSP
Uniprot:	P21815
Entrez:	3381

Family

Belongs to:

No superfamily

Alternative Names

BNSP; Bone sialoprotein 2; Bone sialoprotein; BSP 2; BSP II; BSP; BSP2; BSPII; BSP-II; Cell binding sialoprotein; IBSP; Integrin binding sialoprotein; SP II; SPII; SP-II

Molecular Weight

Mass (kDA):
35.148 kDA

Genomic Context


Human

Location:	4q22.1
Sequence:	4; NC_000004.12 (87799554..87812435)

Subcellular Localizations

Secreted.

Diseases

Neoplasms
Malignant Neoplasms
Neoplasm Metastasis
Tissue Adhesions
Malignant Neoplasm Of Breast
Bone Neoplasms
Metastatic Malignant Neoplasm To The Bone
Mammary Neoplasms
Osteosarcoma
Carcinoma
Hypertrophy
Osteoporosis

Headache
Bone Diseases
Osteopenia
Calcinosis
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Prostate
Prostatic Neoplasms

Pathways

Osteoblast Differentiation
Regeneration
Cell Proliferation
Cell Differentiation
Localization
Bone Resorption
Cell Adhesion
Bone Development
Dentinogenesis
Bone Remodeling
Secretion
Root Development
Pathogenesis

Ossification
Bone Mineralization
Wound Healing
Angiogenesis
Tissue Regeneration
Cell Growth
Osteoblast Proliferation

PTMs

Phosphorylation
Cleavage
Sulphation
Glycosylation
Acetylation

Dephosphorylation
Hydroxylation
Methylation
Prenylation
Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IBSP

References

PMID: 2404984 by Fisher L.W., et al. Human bone sialoprotein. Deduced protein sequence and chromosomal localization.

PMID: 8406493 by Kerr J.M., et al. The human bone sialoprotein gene (IBSP): genomic localization and characterization.

3 Publications of Boster Bone sialoprotein 2 Antibodies & ELISA Kits

PubMed ID: 30988819, Liu B,Xu M,Guo Z,Liu J,Chu X,Jiang H.Interleukin-8 promotes prostate cancer bone...
PubMed ID: 27347083, Effect of kidney-reinforcing and marrow-beneficial Chinese medicine on bone meta...
PubMed ID: 24265840, The Osteogenic Potential of Mesoporous Bioglasses/Silk and Non-Mesoporous Biogla...

*More publications can be found for each product on its corresponding product page