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Hyaluronidase-1 Antibodies
AND HYAL1 ELISA kits, Hyaluronidase-1 Proteins
Many biological assays use antibodies to detect Hyaluronidase-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hyaluronidase-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hyaluronidase-1 antibodies...
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HYAL1 Infographic by Boster Bio
All HYAL1 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
IHC, ICC, WB
$370
Cat # PA2181-1
100 μg/vial
Cat # PA2181-1
100 μg/vial
Human Hyaluronidase1/HYAL1 ELISA Kit PicoKine®
1 Citations 8 Q&As
Human
ELISA
$750
Cat # EK1639
96 wells/kit, with removable strips.
Cat # EK1639
96 wells/kit, with removable strips.
HYAL1 Overview
Facts about Hyaluronidase-1.
Hyaluronidase-1 (HYAL1)
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell development.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | HYAL1 |
| Uniprot: | Q12794 |
| Entrez: | 3373 |
Family
| Belongs to: |
|---|
| glycosyl hydrolase 56 family |
Alternative Names
EC 3.2.1.35; FUS2; HYAL1; HYAL-1; Hyaluronidase 1; Hyaluronoglucosaminidase 1; hyaluronoglucosaminidase-1; LUCA1; luCa-1; LUCA1hyaluronidase-1; Lung carcinoma protein 1; MGC45987; NAT6; plasma hyaluronidase; tumor suppressor LUCA-1
Molecular Weight
Mass (kDA):
48.368 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (50299889..50312951, complement) |
Tissue Specificity
Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node specimens showing tumor invasive tumors cells. Isoform 3, isoform 4, isoform 5 and isoform 6 are expressed in normal bladder and bladder tumor tissues.
Subcellular Localizations
Secreted. Lysosome.
Diseases
- Neoplasms
- Malignant Neoplasms
- Headache
- Neoplasm Metastasis
- Carcinoma
- Tumor Angiogenesis
- Malignant Paraganglionic Neoplasm
- Tissue Adhesions
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Lung Neoplasms
- Malignant Neoplasm Of Urinary Bladder
Pathways
- Angiogenesis
- Cell Cycle
- Cell Growth
- Cell Proliferation
- Localization
- Translation
- Wound Healing
- Cell Adhesion
- Cell Migration
- Cell Cycle Arrest
- Inflammatory Response
- Cell-cell Adhesion
- Glycosylation
PTMs
- Biotinylation
- Cleavage
- Methylation
- Glycosylation
Research Areas
- Immunology
- Inflammation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HYAL1
bosterbio.com/bosterbio-gene-info-cards/HYAL1
References
PMID: 8603390 by Wei M.H., et al. Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: progress toward the isolation of a lung cancer TSG.
PMID: 9223416 by Frost G.I., et al. Purification, cloning, and expression of human plasma hyaluronidase.
1 Publications of Boster Hyaluronidase-1 Antibodies & ELISA Kits
- PubMed ID: 10.1111/febs.14859, Colorectal cancer‐associated ~ 6 kDa hyaluronan serves as a novel biomarker ...
*More publications can be found for each product on its corresponding product page