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Heat shock protein beta-1 Antibodies
AND HSPB1 ELISA kits, Heat shock protein beta-1 Proteins
Many biological assays use antibodies to detect Heat shock protein beta-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Heat shock protein beta-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Heat shock protein beta-1 antibodies...
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HSPB1 Infographic by Boster Bio
All HSPB1 Products
Product
Figures
Specificity
Applications
Price
Human HSP27/HSPB1/Heat Shock Protein 27 ELISA Kit PicoKine®
1 Citations 9 Q&As
Human
ELISA
$380
Cat # EK0881
96wells/kit, with removable strips.
Cat # EK0881
96wells/kit, with removable strips.
Anti-HSP27 Hspb1 Monoclonal Antibody
1 Citations
Human, Mouse, Rabbit, Rat
IHC, ICC, WB
$370
Cat # MA1048
100 μg/vial
Cat # MA1048
100 μg/vial
Anti-Hsp27/HSPB1 Antibody Picoband®
1 Citations 1 Q&As
Human
Flow Cytometry, IP, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9237
100 μg/vial
Cat # PB9237
100 μg/vial
Human, Mouse, Rat
IP, WB
$370
Cat # P00676-1
100 μl
Cat # P00676-1
100 μl
Human
IP, IF, IHC, ICC, WB
$370
Cat # P00676
100 μl
Cat # P00676
100 μl
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00676-2
100 μl
Cat # M00676-2
100 μl
Anti-Hsp27/Hspb1 Antibody Picoband®
2 Citations
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A00676
100 μg/vial
Cat # A00676
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1287
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1287
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2432
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2432
1 kit, containing two 96-well plates and all necessary reagents
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00676-5
100 μg/vial
Cat # M00676-5
100 μg/vial
Human
Flow Cytometry
$515
Cat # M00676-Dyl488
100 μg/vial
Cat # M00676-Dyl488
100 μg/vial
HSPB1 Overview
Facts about Heat shock protein beta-1.
Heat shock protein beta-1 (HSPB1)
Small heat shock protein which functions as a molecular chaperone probably keeping denatured proteins in a folding- competent state (PubMed:10383393, PubMed:20178975). Plays a role in stress resistance and actin organization (PubMed:19166925).
Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PubMed:23728742). .
Gene Information
| Human | |
|---|---|
| Gene Name: | HSPB1 |
| Uniprot: | P04792 |
| Entrez: | 3315 |
Family
| Belongs to: |
|---|
| small heat shock protein (HSP20) family |
Alternative Names
28 kDa heat shock protein; DKFZp586P1322; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; heat shock 27kD protein 1; heat shock 27kDa protein 1; heat shock protein beta-1; HMN2B; HS.76067; HSP25; HSP27; HSP27HSP 27; HSP28CMT2F; HSPB1; SRP27; Stress-responsive protein 27
Molecular Weight
Mass (kDA):
22.783 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q11.23 |
| Sequence: | 7; NC_000007.14 (76302673..76304292) |
Tissue Specificity
Detected in all tissues tested: skeletal muscle, heart, aorta, large intestine, small intestine, stomach, esophagus, bladder, adrenal gland, thyroid, pancreas, testis, adipose tissue, kidney, liver, spleen, cerebral cortex, blood serum and cerebrospinal fluid. Highest levels are found in the heart and in tissues composed of striated and smooth muscle.
Subcellular Localizations
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Ischemia
- Inflammation
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Physiological Stress
- Neurodegenerative Disorders
- Adenocarcinoma
- Tissue Adhesions
Interacting Proteins
- BAG3
- CALR
- CRYAB
- DAXX
- DFFA
- EFTUD2
- EGFR
- EIF4A2
- EIF4G2
- FKBP4
Pathways
- Cell Death
- Localization
- Pathogenesis
- Cell Cycle
- Cell Proliferation
- Cell Growth
- Transport
- Secretion
- Drug Resistance
- Cell Migration
- Translation
- Aging
- Response To Heat
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
- Ubiquitination
- Reduction
- Oxidation
- Methylation
Research Areas
- Cancer
- Cell Biology
- Cell Cycle and Replication
- Golgi Apparatus Markers
- Membrane Trafficking and Chaperones
- Neuroscience
- Phospho-Specific
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSPB1
bosterbio.com/bosterbio-gene-info-cards/HSPB1
References
PMID: 3714473 by Hickey E., et al. Sequence and organization of genes encoding the human 27 kDa heat shock protein.
PMID: 2243808 by Carper S.W., et al. cDNA sequence of a human heat shock protein HSP27.
5 Publications of Boster Heat shock protein beta-1 Antibodies & ELISA Kits
- PubMed ID: 10.3760/cma.j.issn.0366-6999.2011.15.018, Expression of heat shock protein 27 in the esophageal tissue of rats with reflux...
- PubMed ID: 10.1007/s11596-009-0323-x, Effects of mitogen-activated protein kinase signal pathway on heat shock protein...
- PubMed ID: 10.1002/jcb.23293, LRRC4 inhibits the proliferation of human glioma cells by modulating the express...
- PubMed ID: 29404146, Serum Heat Shock Protein Levels and the Relationship of Heat Shock Proteins with...
- PubMed ID: 26117090, Wu Yw, Hao T, Kou Xx, Gan Yh, Ma Xc. Arch Oral Biol. 2015 Sep;60(9):1310-8. Doi:...
*More publications can be found for each product on its corresponding product page