HPGD Antibodies

AND HPGD ELISA kits, HPGD Proteins

Many biological assays use antibodies to detect HPGD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HPGD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HPGD antibodies...

We validate the specificity of these antibodies to HPGD by testing them on tissues known to express HPGD positively and negatively. Browse below to find the HPGD antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HPGD Infographic by Boster Bio

All HPGD Products

Product

Figures

Specificity

Applications

Price

Anti-PGDH Rabbit Monoclonal Antibody

7 Q&As

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M02686
100 μl

Human 15-PGDH/HPGD Recombinant Protein

SDS-PAGE

$250
Cat # PROTP15428
Starting from 10ug

Mouse Hpgd Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ8VCC1
Starting from 20ug

Prostaglandin dehydrogenase 1 (HPGD) (NM_000860) Human Over-expression Lysate

Human

$628
Cat # LS003248
100 µg

HPGD Overview

Facts about 15-hydroxyprostaglandin dehydrogenase [NAD(+)].

HPGD 3D structure. Source: alphafold

15-hydroxyprostaglandin dehydrogenase [NAD(+)] (HPGD)

Prostaglandin inactivation. Contributes to the regulation of events which are under the control of prostaglandin levels.

Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.

Gene Information

Human
Gene Name:	HPGD
Uniprot:	P15428
Entrez:	3248

Family

Belongs to:

short-chain dehydrogenases/reductases (SDR) family

Alternative Names

15-hydroxyprostaglandin dehydrogenase [NAD+]; 15PGDH; 15-PGDH; EC 1.1.1; EC 1.1.1.141; HPGD; hydroxyprostaglandin dehydrogenase 15-(NAD); NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; PGDH1; PGDH1PGDH; Prostaglandin dehydrogenase 1; SDR36C1; short chain dehydrogenase/reductase family 36C, member 1

Molecular Weight

Mass (kDA):
28.977 kDA

Genomic Context


Human

Location:	4q34.1
Sequence:	4; NC_000004.12 (174490175..174522898, complement)

Tissue Specificity

Detected in colon epithelium (at protein level).

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Osteoarthropathy, Primary Hypertrophic
Hypertrophy
Clubbing
Osteoarthropathy
Clubbed Fingers
Colorectal Cancer
Colorectal Neoplasms
Carcinoma
Cell Transformation, Neoplastic
Pachyderma

Adenoma
Hereditary Diseases
Carcinogenesis
Metastatic Malignant Neoplasm To The Lymph Node
Osteoarthropathy, Secondary Hypertrophic
Adenocarcinoma
Prostatic Neoplasms

Pathways

Transport
Pathogenesis
Ovulation
Reverse Transcription
Cell Cycle
Cell Growth
Luteinization
Rna Interference
Keratinization
Cell Migration
Keratinocyte Differentiation
Vasculogenesis
Chemotaxis

Cell Differentiation
Telomere Maintenance
Diestrus
Estrus
Response To Hydrogen Peroxide
Luteolysis
Dna Methylation

PTMs

Methylation

Research Areas

Cancer
Immunology
Innate Immunity

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HPGD

References

PMID: 2337593 by Krook M., et al. Purification and structural characterization of placental NAD(+)- linked 15-hydroxyprostaglandin dehydrogenase. The primary structure reveals the enzyme to belong to the short-chain alcohol dehydrogenase family.

PMID: 1697582 by Ensor C.M., et al. Cloning and sequence analysis of the cDNA for human placental NAD(+)- dependent 15-hydroxyprostaglandin dehydrogenase.