HESX1 Antibodies

AND HESX1 ELISA kits, HESX1 Proteins

Many biological assays use antibodies to detect HESX1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HESX1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HESX1 antibodies...

We validate the specificity of these antibodies to HESX1 by testing them on tissues known to express HESX1 positively and negatively. Browse below to find the HESX1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HESX1 Infographic by Boster Bio

All HESX1 Products

Product

Figures

Specificity

Applications

Price

Anti-HESX1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A04357
100ul

HESX1 (NM_003865) Human Recombinant Protein

$1249
Cat # PROTQ9UBX0
20 µg

HESX1 (NM_003865) Human Over-expression Lysate

Human

$628
Cat # LS008820
100 µg

HESX1 Overview

Facts about Homeobox expressed in ES cells 1.

HESX1 3D structure. Source: alphafold

Homeobox expressed in ES cells 1 (HESX1)

Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and adrenal gland. Possible transcriptional repressor.

Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation.

Gene Information

Human
Gene Name:	HESX1
Uniprot:	Q9UBX0
Entrez:	8820

Family

Belongs to:

ANF homeobox family

Alternative Names

CPHD5; hAnf; HESX homeobox 1; homeobox expressed in ES cells 1; Homeobox protein ANF; MGC138294; Rathke pouch homeobox; RPXES cell expressed 1

Molecular Weight

Mass (kDA):
21.409 kDA

Genomic Context


Human

Location:	3p14.3
Sequence:	3; NC_000003.12 (57197838..57227643, complement)

Subcellular Localizations

Nucleus.

Diseases

Pituitary Diseases
Septo-optic Dysplasia
Dysplasia
Hypopituitarism
Hypoplasia
Somatotropin Deficiency
Dwarfism
Pituitary Gland Hypoplasia
Optic Nerve Hypoplasia
Growth Disorders
Hypothyroidism
Holoprosencephaly

Nervousness
Congenital Absence
Congenital Abnormality
Panhypopituitarism
Neoplasms
Anophthalmos
Isolated Somatotropin Deficiency

Interacting Proteins

KDM1A
PRMT6

Pathways

Pathogenesis
Forebrain Development
Gastrulation
Secretion
Cell Differentiation
Pituitary Gland Development
Gland Development
Brain Development
Cell Proliferation
Localization
Cell Adhesion
Translation
Eye Development

Forebrain Morphogenesis
Stem Cell Differentiation
Cell Fate Specification
Mrna Processing
Gonad Development
Corpus Callosum Development
Neural Plate Development

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HESX1

References

PMID: 9620767 by Dattani M.T., et al. Mutations in the homeobox gene HESX1/Hesx1 associated with septo- optic dysplasia in human and mouse.

PMID: 9373136 by Kazanskaya O.V., et al. Anf: a novel class of vertebrate homeobox genes expressed at the anterior end of the main embryonic axis.