Hyaluronidase-3 Antibodies

AND HYAL3 ELISA kits, Hyaluronidase-3 Proteins

Many biological assays use antibodies to detect Hyaluronidase-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hyaluronidase-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hyaluronidase-3 antibodies...

We validate the specificity of these antibodies to Hyaluronidase-3 by testing them on tissues known to express HYAL3 positively and negatively. Browse below to find the HYAL3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HYAL3 Infographic by Boster Bio

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Anti-Hyaluronidase-3 HYAL3 Antibody Picoband®

7 Q&As

Human, Mouse

IHC, WB

$370
Cat # PA1856
100 μg/vial

HYAL3 Overview

Facts about Hyaluronidase-3.

HYAL3 3D structure. Source: alphafold

Hyaluronidase-3 (HYAL3)

Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm.

Involved in follicular atresia, the breakdown of immature ovarian follicles which aren't selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage.

Gene Information

Human
Gene Name:	HYAL3
Uniprot:	O43820
Entrez:	8372

Family

Belongs to:

glycosyl hydrolase 56 family

Alternative Names

EC 3.2.1.35; HYAL-3; hyaluronidase-3; hyaluronoglucosaminidase 3; Hyaluronoglucosaminidase-3; LUCA14; LuCa-3; LUCA3LUCA-3; Lung carcinoma protein 3; Minna14

Molecular Weight

Mass (kDA):
46.501 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (50292832..50299405, complement)

Tissue Specificity

Expressed in sperm (PubMed:20586096). Highly expressed in epidermis of the skin, where it is expressed intracellularily in the deep horny layer (at protein level) (PubMed:21699545). Bone marrow, testis and kidney (PubMed:10493834).

Subcellular Localizations

Secreted. Cell membrane. Cytoplasmic vesicle, secretory vesicle, acrosome. Endoplasmic reticulum. Early endosome. Mostly present in low-density vesicles. Low levels in higher density vesicles of late endosomes and lysosomes. Localized in punctate cytoplasmic vesicles and in perinuclear structures, but does not colocalize with LAMP1. Localized on the plasma membrane over the acrosome and on the surface of the midpiece of the sperm tail.