HTR2A Antibodies

AND HTR2A ELISA kits, HTR2A Proteins

Many biological assays use antibodies to detect HTR2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HTR2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HTR2A antibodies...

We validate the specificity of these antibodies to HTR2A by testing them on tissues known to express HTR2A positively and negatively. Browse below to find the HTR2A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HTR2A Infographic by Boster Bio

All HTR2A Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-5HT2A Receptor/HTR2A Antibody Picoband®

1 Q&As

Human, Rat

IHC, WB

$370
Cat # PB9599
100 μg/vial

Anti-5HT2A Receptor/HTR2A Antibody Picoband®

4 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # PA1373
100 μg/vial

Anti-Htr2a Antibody (N-term)

Mouse

IHC-P, WB

$299
Cat # M01005
80 µl

HTR2A Overview

Facts about 5-hydroxytryptamine receptor 2A.

HTR2A 3D structure. Source: alphafold

5-hydroxytryptamine receptor 2A (HTR2A)

Also functions as a receptor for a variety of drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4- iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that activates signaling through guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538).

Beta-arrestin family members inhibit signaling through G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system which modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores (PubMed:18703043, PubMed:28129538).

Gene Information

Human
Gene Name:	HTR2A
Uniprot:	P28223
Entrez:	3356

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

5-HT2 receptor; 5-HT-2; 5HT2A; 5-HT2A; 5-HT-2A; 5-hydroxytryptamine (serotonin) receptor 2A; 5-hydroxytryptamine receptor 2A; HTR2,5-HT2A; HTR2A; serotonin 5-HT-2A receptor; Serotonin receptor 2A

Molecular Weight

Mass (kDA):
52.603 kDA

Genomic Context


Human

Location:	13q14.2
Sequence:	13; NC_000013.11 (46831542..46897076, complement)

Tissue Specificity

Detected in brain cortex (at protein level). Detected in blood platelets.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, axon. Cytoplasmic vesicle. Membrane, caveola. Cell junction, synapse, presynapse.