HSD17B4 Antibodies

AND HSD17B4 ELISA kits, HSD17B4 Proteins

Many biological assays use antibodies to detect HSD17B4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HSD17B4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HSD17B4 antibodies...

We validate the specificity of these antibodies to HSD17B4 by testing them on tissues known to express HSD17B4 positively and negatively. Browse below to find the HSD17B4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HSD17B4 Infographic by Boster Bio

All HSD17B4 Products

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Specificity

Applications

Price

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 Antibody Picoband®

1 Citations 1 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # PA1727
100 μg/vial

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 Antibody Picoband®

1 Citations 6 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # A02923
100 μg/vial

Anti-Hydroxysteroid (17 beta) Dehydrogenase 4 (HSD17B4) Mouse Monoclonal Antibody [Clone ID: OTI4C4]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M02923
100 µl

HSD17B4 Overview

Facts about Peroxisomal multifunctional enzyme type 2.

HSD17B4 3D structure. Source: alphafold

Peroxisomal multifunctional enzyme type 2 (HSD17B4)

Bifunctional enzyme acting on the peroxisomal beta- oxidation pathway for fatty acids. Catalyzes the formation of 3- ketoacyl-CoA intermediates from both straight-chain and 2-methyl- branched-chain fatty acids.

Gene Information

Human
Gene Name:	HSD17B4
Uniprot:	P51659
Entrez:	3295

Family

Belongs to:

short-chain dehydrogenases/reductases (SDR) family

Alternative Names

12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; 7-alpha; D-bifunctional protein; EDH17B4; hydroxysteroid (17-beta) dehydrogenase 4; MPF-2; peroxisomal multifunctional enzyme type 2,17-beta-HSD IV; peroxisomal multifunctional protein 2,17beta-estradiol dehydrogenase type IV; peroxisomal; short chain dehydrogenase/reductase family 8C, member 1,3-alpha

Molecular Weight

Mass (kDA):
79.686 kDA

Genomic Context


Human

Location:	5q23.1
Sequence:	5; NC_000005.10 (119452497..119542332)

Tissue Specificity

Present in many tissues with highest concentrations in liver, heart, prostate and testis.

Subcellular Localizations

Peroxisome.

Diseases

Peroxisomal Disorders
Protein Deficiency
Malignant Neoplasms
Zellweger Syndrome
Adrenoleukodystrophy
Neoplasms
Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Refsum Disease
Malignant Neoplasm Of Breast
Mammary Neoplasms
Muscle Hypotonia

Neoplasms, Germ Cell And Embryonal
Testicular Germ Cell Tumor
Sensorineural Hearing Loss (disorder)
Carcinoma
Gonadal Dysgenesis Xx Type Deafness
Germ Cell Tumor

Pathways

Fatty Acid Beta-oxidation
Conjugation
Methylation
Dna Methylation
Fatty Acid Oxidation
Transport
Cell Growth
Pathogenesis
Aging
Brain Development
Oxidative Phosphorylation
Dosage Compensation
Spermatogenesis

Myelination
Mrna Transcription
Fatty Acid Transport
Gliogenesis
Lipid Homeostasis
Cell Differentiation
Protein Import

PTMs

Oxidation
Methylation
Hydroxylation

Cleavage
Phosphorylation
Carboxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSD17B4

References

PMID: 7487879 by Adamski J., et al. Molecular cloning of a novel widely expressed human 80 kDa 17 beta- hydroxysteroid dehydrogenase IV.

PMID: 9089413 by Jiang L.L., et al. Structure of D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein.

1 Publications of Boster HSD17B4 Antibodies & ELISA Kits

PubMed ID: 30453308, Correlation between HSD17B4 expression in rat liver cancer tissues and inflammat...

*More publications can be found for each product on its corresponding product page