HSD17B2 Antibodies

AND HSD17B2 ELISA kits, HSD17B2 Proteins

Many biological assays use antibodies to detect HSD17B2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HSD17B2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HSD17B2 antibodies...

We validate the specificity of these antibodies to HSD17B2 by testing them on tissues known to express HSD17B2 positively and negatively. Browse below to find the HSD17B2 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: DNAJB2

HSD17B2 Infographic by Boster Bio

All HSD17B2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HSD17B2 Antibody Picoband®

6 Q&As

Human

IHC, WB

$370
Cat # PA1604
100 μg/vial

Anti-HSD17B2 Antibody Picoband®

Human

Flow Cytometry, WB

$370
Cat # A02506
100 μg/vial

Anti-HSD17B2 Mouse Monoclonal Antibody [Clone ID: OTI3E9]

Human

Flow Cytometry, WB

$523
Cat # M02506
100 µl

HSD17B2 (NM_002153) Human Over-expression Lysate

Human

$628
Cat # LS003294
100 µg

Anti-HSD17B2 Antibody Picoband®

Human, Mouse

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A02506-1
100 µg/vial

HSD17B2 Overview

Facts about Estradiol 17-beta-dehydrogenase 2.

HSD17B2 3D structure. Source: alphafold

Estradiol 17-beta-dehydrogenase 2 (HSD17B2)

Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity.

Uses NADH while EDH17B3 utilizes NADPH. .

Gene Information

Human
Gene Name:	HSD17B2
Uniprot:	P37059
Entrez:	3294

Family

Belongs to:

short-chain dehydrogenases/reductases (SDR) family

Alternative Names

17-beta-hydroxysteroid dehydrogenase type 2; 20 alpha-hydroxysteroid dehydrogenase; E2DH; EC 1.1.1.62,17-beta-HSD 2; EC 1.1.1.63; EDH17B220-alpha-HSD; estradiol 17-beta-dehydrogenase 2; HSD17; hydroxysteroid (17-beta) dehydrogenase 2; Microsomal 17-beta-hydroxysteroid dehydrogenase; SDR9C2; short chain dehydrogenase/reductase family 9C, member 2; Testosterone 17-beta-dehydrogenase

Molecular Weight

Mass (kDA):
42.785 kDA

Genomic Context


Human

Location:	16q23.3
Sequence:	16; NC_000016.10 (82035253..82098534)

Subcellular Localizations

Membrane; Single-pass type II membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Endometrial Polyp
Mammary Neoplasms
Endometriosis, Site Unspecified
Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Endometrial Neoplasms
Endometrial Carcinoma
Steroid Sulfatase Deficiency Disease
Carcinoma

Adenocarcinoma
Growth Retardation
Infertility
Osteoporosis
Colorectal Neoplasms
Inflammation
Colorectal Cancer

Pathways

Pathogenesis
Secretion
Localization
Methylation
Lung Development
Spermatogenesis
Cell Proliferation
Menopause
Decidualization
Prolactin Secretion
Transport
Tricarboxylic Acid Cycle
Gene Silencing

Osteoblast Differentiation
Aging
Brain Development
Hepatocyte Proliferation
Cell Maturation
Regulation Of Hepatocyte Proliferation
Bone Development

PTMs

Methylation

Reduction

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSD17B2

References

PMID: 8099587 by Wu L., et al. Expression cloning and characterization of human 17 beta- hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity.

PMID: 7546291 by Labrie Y., et al. The human type II 17 beta-hydroxysteroid dehydrogenase gene encodes two alternatively spliced mRNA species.