Protein Hook homolog 1 Antibodies

AND HOOK1 ELISA kits, Protein Hook homolog 1 Proteins

Many biological assays use antibodies to detect Protein Hook homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein Hook homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein Hook homolog 1 antibodies...

We validate the specificity of these antibodies to Protein Hook homolog 1 by testing them on tissues known to express HOOK1 positively and negatively. Browse below to find the HOOK1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HOOK1 Infographic by Boster Bio

All HOOK1 Products

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Price

Anti-Protein Hook homolog 1 HOOK1 Antibody

Human, Mouse, Rat

$405
Cat # A06755
100ul

HOOK1 (NM_015888) Human Recombinant Protein

$813
Cat # PROTQ9UJC3
20 µg

HOOK1 (NM_015888) Human Over-expression Lysate

Human

$628
Cat # LS051361
100 µg

HOOK1 Overview

Facts about Protein Hook homolog 1.

HOOK1 3D structure. Source: alphafold

Protein Hook homolog 1 (HOOK1)

Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum with regard to the membrane skeleton (By similarity).

Part of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) (PubMed:18799622).

Gene Information

Human
Gene Name:	HOOK1
Uniprot:	Q9UJC3
Entrez:	51361

Family

Belongs to:

hook family

Alternative Names

hHK1; HK1h-hook1; hook homolog 1 (Drosophila); MGC10642; protein Hook homolog 1

Molecular Weight

Mass (kDA):
84.648 kDA

Genomic Context


Human

Location:	1p32.1
Sequence:	1; NC_000001.11 (59814922..59876370)

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton. Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, multivesicular bodies (MVBs), lysosomes, or mitochondria (By similarity). Often found in close association with microtubules (By similarity). Does not associate with the Golgi complex. During spermiogenesis, it localizes to the manchette in spermatids from steps 8-10. It is also present between the microtubule manchette and the nucleus. During manchette elongation, it is preferentially localized to the nuclear ring of the manchette,