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HNRNPD Antibodies
AND HNRNPD ELISA kits, HNRNPD Proteins
Many biological assays use antibodies to detect HNRNPD, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HNRNPD in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HNRNPD antibodies...
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HNRNPD Infographic by Boster Bio
All HNRNPD Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$540
Cat # EKC2292
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2292
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A09982-1
100 μg/vial
Cat # A09982-1
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A02895S83
100ul
Cat # A02895S83
100ul
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M09982
100 μg/vial
Cat # M09982
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M09982-1
100 μg/vial
Cat # M09982-1
100 μg/vial
HNRNPD Overview
Facts about Heterogeneous nuclear ribonucleoprotein D0.
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD)
Binds with higher affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of several proto- oncogenes and cytokine mRNAs. Also binds to double- and single- stranded DNA sequences in a specific manner and functions a transcription factor.
Each of the RNA-binding domains namely may bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'- TTAGGG-3' repeats.
Gene Information
| Human | |
|---|---|
| Gene Name: | HNRNPD |
| Uniprot: | Q14103 |
| Entrez: | 3184 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
AUF1A; heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein1, 37kDa); heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA-binding protein1, 37kD); heterogeneous nuclear ribonucleoprotein D0; hnRNPD0; type A
Molecular Weight
Mass (kDA):
38.434 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q21.22 |
| Sequence: | 4; NC_000004.12 (82352498..82373996, complement) |
Subcellular Localizations
Nucleus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Cytoplasmic localization oscillates diurnally.
Diseases
- Cell Transformation, Neoplastic
- Neoplasms
- Sarcoma
- Malignant Neoplasms
- Speech Delay
- Sarcoma, Experimental
- Lymphoma
- Cytogenetic Abnormality
- Contact Hypersensitivity
- Pathologic Neovascularization
- Pruritus
Interacting Proteins
- EIF4G1
- HNRNPA2B1
- HNRNPU
- IGF2BP2
- ING4
- LDHAL6B
- PABPC1
- SFN
- SYNCRIP
- YBX1
Pathways
- Hyperphosphorylation
- Cell Proliferation
- Hypersensitivity
- Regulation Of Mrna Stability
- Oncogenesis
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HNRNPD
bosterbio.com/bosterbio-gene-info-cards/HNRNPD
References
PMID: 7673195 by Kajita Y., et al. The UUAG-specific RNA binding protein, heterogeneous nuclear ribonucleoprotein D0. Common modular structure and binding properties of the 2xRBD-Gly family.
PMID: 9615222 by Dempsey L.A., et al. The human HNRPD locus maps to 4q21 and encodes a highly conserved protein.