Hexokinase-1 Antibodies

Hexokinase-1 (HK1)

Gene Information

Human
Gene Name:	HK1
Uniprot:	P19367
Entrez:	3098

Family

Belongs to:
hexokinase family

Alternative Names

Brain form hexokinase; EC 2.7.1; EC 2.7.1.1; glycolytic enzyme; Hexokinase 1; Hexokinase type I; hexokinase-1; HK I; HK1; HK1-ta; HK1-tb; HK1-tc; HKI; HXK1

Molecular Weight

Mass (kDA):
102.486 kDA

Genomic Context

Human
Location:	10q22.1
Sequence:	10; NC_000010.11 (69269991..69401882)

Tissue Specificity

Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.

Subcellular Localizations

Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasm, cytosol. The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331).

Diseases

• Neoplasms
• Malignant Neoplasms
• Carcinoma
• Nasopharyngeal Neoplasms
• Skin Neoplasms
• Papilloma
• Cancer Of Nasopharynx
• Carcinogenesis
• Hyperplasia
• Malignant Paraganglionic Neoplasm
• Cell Transformation, Neoplastic

• Malignant Neoplasm Of Nasopharynx
• Hyperkeratosis
• Diabetes Mellitus
• Diabetes Mellitus, Non-insulin-dependent
• Cell Invasion
• Glioma

Interacting Proteins

• SRC
• Src
• VDAC1

Pathways

• Glycolysis
• Cell Death
• Localization
• Cell Cycle
• Mating
• Cell Proliferation
• Transport
• Angiogenesis
• Secretion
• Pathogenesis
• Glucose Transport
• Methylation
• Cell Growth

• Sperm Motility
• Aging
• Keratinocyte Differentiation
• Cell Migration
• Gluconeogenesis
• Spermatogenesis
• Glucose Homeostasis

PTMs

• Phosphorylation
• Cleavage
• Methylation

• Reduction
• Biotinylation
• Deamination

• Oxidation

Research Areas

• Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HK1

Boster Bio: Best Uses Of The HK1 Marker

The primary antibodies produced by Boster are highly reliable for scientific research as well as other uses. Boster's antibodies are utilized in various fields such as biomedical research and animal welfare. They also play a role in plant and animal agriculture. Scientists are able to submit their research findings in various applications and samples. Researchers can earn product credits for their research. Boster bio: Best Uses of the HK1 Marker gives scientists from around the world an opportunity to submit their results.

Boster's primary antibodies are regarded as reliable by the research community

Whether you are looking for high-affinity antibodies for Western Blotting, ELISA, FC, or Immunohistochemistry, you can count on Boster Bio to deliver. All Boster's products can be verified and tested to provide the best results in your studies. Boster products are guaranteed to be top quality throughout the duration of the reagent. This is the reason why the research community trusts Boster.

In addition , to providing high-quality secondary and primary antibodies, Boster is an ISO certified company with ISO 9001 certification. Their products are utilized in research and development laboratories around the world. In addition to providing high-quality primary antibodies Boster also provides custom-made antibody. Because their products are custom-made and tested, Boster's research community-respected primary antibodies are available to purchase. For high-quality research Boster's products are readily available at affordable prices.

Furthermore, reproducibility is essential in the scientific community. For this reason, Boster's primary antibodies are dependable and are trusted by researchers. The Quality Assurance Program was created by Boster in 2012 to ensure consistent and reproducible quality of its antibodies. It is based on the analysis of hundreds and thousands of antibody citations, and is supported by researchers.

Rockland can provide you with the monoclonal or multiclonal antibodies you require. Rockland is a specialist in phosho-site-specific antibodies and other primary antibodies. Their scientists are well-trained in both polyclonal and monoclonal antibody techniques. And their antibodies are suitable for most immunological methods, such as Western Blotting and immunohistochemistry.

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Boster's primary antibody is manufactured by a reputable corporation

Boster Bio is a reliable source of high-quality primary antibodies. Boster Bio manufactures antibodies for ELISA, WB, IHC, FC, and RT-PCR. Boster Bio manufactures reagents which are rigorously tested and optimized for ELISA or WB applications. Many of the products offered by Boster Bio have been tested and come with the Boster Quality Guarantee. You can also get secondary antibodies free of charge when you purchase a primary antibody.

One of the most important aspects of high-quality primary antibodies is the fact that they are produced by a reputable business. Boster is committed quality and customer service. It ensures that its products meet the highest requirements. The company manufactures its primary antibodies and ELISA kits at its own facilities and has a strict control system to ensure the efficiency and quality of its products. The company provides an unconditional money-back guarantee. You can always check the guarantee of the manufacturer if you are unsure about the quality of a primary antigen.

This list includes suppliers who have published more than 60000 articles within the last five years. This list includes high-quality suppliers, whose products are frequently cited in scientific papers. The list is regularly updated and highlights the top suppliers. The company produces high-quality antibody to ensure the highest standards of medical research and applications. It also produces high quality antibodies at the most affordable price.

Quality primary antibodies should be of high purity. Although the Fc-stalk is very stable, it is essential in the antibody's interactions with cell receptors and effector molecules. The quality of the primary antibodies is determined by their affinity and specificity. The greater the affinity is, the higher. The lower the specificity, less specific the antibody is. A high-quality primary antibody should not have any difficulties in detecting, purifying, and measuring the target antigen.

Primary antibodies are the primary component of any research. They are the basic components of experiments and tests. They are the main components of Western Blotting, immunohistochemistry, histopathology tests, and other tests. Enzyme-linked immunosorbent assay (ELISA) uses primary antibodies and is a form of an enzyme-mediated test for immunoassay. Flow cytometry determines the number of specific cell types of interest in an individual sample.

Secondary antibodies are another essential component of a well-planned research project. They identify the expression of target proteins in cells or tissues. Primary antibodies are produced using the specificity of the secondary antibodies, and the latter recognizes a particular region on the protein of interest. The signal is amplified when multiple secondary antibodies bind to an antibody that is a primary. Secondary antibodies are necessary for many experiments, including immunoassays.

Boster's antibodies can be used in many research areas

Bethyl has been a pioneer in antibody production for over 30 years. Its products are used in research, manufacture analyses, as well as identification of a broad range of substances. Boster's has more than 12,000 available antibodies. To learn more, contact Bethyl today. And don't be a fool to look over their extensive list of antibodies to use in your next project.