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- Table of Contents
Facts about Hexokinase-1.
Human | |
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Gene Name: | HK1 |
Uniprot: | P19367 |
Entrez: | 3098 |
Belongs to: |
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hexokinase family |
Brain form hexokinase; EC 2.7.1; EC 2.7.1.1; glycolytic enzyme; Hexokinase 1; Hexokinase type I; hexokinase-1; HK I; HK1; HK1-ta; HK1-tb; HK1-tc; HKI; HXK1
Mass (kDA):
102.486 kDA
Human | |
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Location: | 10q22.1 |
Sequence: | 10; NC_000010.11 (69269991..69401882) |
Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.
Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasm, cytosol. The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331).
PMID: 3207429 by Nishi S., et al. Human hexokinase: sequences of amino- and carboxyl-terminal halves are homologous.
PMID: 9531504 by Ruzzo A., et al. Structure of the human hexokinase type I gene and nucleotide sequence of the 5' flanking region.