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Protein Hikeshi Antibodies

AND HIKESHI ELISA kits, Protein Hikeshi Proteins

Many biological assays use antibodies to detect Protein Hikeshi, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein Hikeshi in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein Hikeshi antibodies...

We validate the specificity of these antibodies to Protein Hikeshi by testing them on tissues known to express HIKESHI positively and negatively. Browse below to find the HIKESHI antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HIKESHI Infographic by Boster Bio

HIKESHI protein infographic

All HIKESHI Products

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Applications

Price

C11orf73 (HIKESHI) (NM_016401) Human Recombinant Protein

$813
Cat # PROTQ53FT3
20 µg

C11orf73 (HIKESHI) (NM_016401) Human Over-expression Lysate

Human

$628
Cat # LS051501
100 µg

HIKESHI Overview

Facts about Protein Hikeshi.

HIKESHI 3D structure

HIKESHI 3D structure. Source: alphafold

Protein Hikeshi (HIKESHI)

Acts as a specific nuclear import carrier for HSP70 proteins after heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is needed to protect cells from heat shock damages.

Does not translocate ADP-bound HSP70 proteins into the nucleus. .

Gene Information

Human
Gene Name:	HIKESHI
Uniprot:	Q53FT3
Entrez:	51501

Gene Information

Family

Belongs to:

OPI10 family

Family

Alternative Names

Protein Hikeshi

Molecular Weight

Mass (kDA):
21.628 kDA

Molecular Weight

Genomic Context


Human

Location:	11q14.2
Sequence:	11; NC_000011.10 (86302229..86345943)

Subcellular Localizations

Cytoplasm. Cytoplasm, cytosol. Nucleus.

Subcellular Localization

Diseases

Leukodystrophy, hypomyelinating, 13 (HLD13)

Disease

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For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HIKESHI

References

PMID: 22541429 by Kose S., et al. Hikeshi, a nuclear import carrier for hsp70s, protects cells from heat shock-induced nuclear damage.

PMID: 25760597 by Song J., et al. Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70s.