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- Table of Contents
3 Q&As
Facts about Hepatoma-derived growth factor.
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Human | |
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Gene Name: | HDGF |
Uniprot: | P51858 |
Entrez: | 3068 |
Belongs to: |
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HDGF family |
FLJ96580; HDGF; hepatoma-derived growth factor (high-mobility group protein 1-like); hepatoma-derived growth factor; High mobility group protein 1-like 2; HMG-1L2; HMG1L2DKFZp686J1764; HuHGF
Mass (kDA):
26.788 kDA
Human | |
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Location: | 1q23.1 |
Sequence: | 1; NC_000001.11 (156742107..156752448, complement) |
Ubiquitous.
[Isoform 1]: Nucleus. Cytoplasm. Secreted, extracellular exosome. Secreted by exosomes and is located inside the exosome (PubMed:27926477). May also be secreted as free protein via an as yet unknown pathway (PubMed:27926477).; [Isoform 2]: Nucleus. Cytoplasm. Secreted, extracellular exosome. Secreted by exosomes and is located on the outer exosome surface.; [Isoform 3]: Nucleus. Cytoplasm. Secreted, extracellular exosome. Secreted by exosomes and is located on the outer exosome surface.
PMID: 7929202 by Nakamura H., et al. Molecular cloning of complementary DNA for a novel human hepatoma- derived growth factor. Its homology with high mobility group-1 protein.
PMID: 11751870 by Kishima Y., et al. Hepatoma-derived growth factor stimulates cell growth after translocation to the nucleus by nuclear localization signals.