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Histone deacetylase 6 Antibodies
AND HDAC6 ELISA kits, Histone deacetylase 6 Proteins
Many biological assays use antibodies to detect Histone deacetylase 6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone deacetylase 6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone deacetylase 6 antibodies...
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HDAC6 Infographic by Boster Bio
All HDAC6 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # PB9628
100 μg/vial
Cat # PB9628
100 μg/vial
Human
IP, IF, IHC, ICC, WB
$370
Cat # M00595
100 μl
Cat # M00595
100 μl
Human, Mouse
ELISA
$480
Cat # EKC1266
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1266
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2263
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2263
1 kit, containing two 96-well plates and all necessary reagents
Dog, Human, Monkey, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M00595-2
100 µl
Cat # M00595-2
100 µl
Human, Monkey
Flow Cytometry, IHC, WB
$523
Cat # M00595-1
100 µl
Cat # M00595-1
100 µl
HDAC6 Overview
Facts about Histone deacetylase 6.
Histone deacetylase 6 (HDAC6)
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Gene Information
| Human | |
|---|---|
| Gene Name: | HDAC6 |
| Uniprot: | Q9UBN7 |
| Entrez: | 10013 |
Family
| Belongs to: |
|---|
| histone deacetylase family |
Alternative Names
EC 3.5.1.98; HD6FLJ16239; histone deacetylase 6; JM21; KIAA0901
Molecular Weight
Mass (kDA):
131.419 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp11.23 |
| Sequence: | X; NC_000023.11 (48801398..48824982) |
Subcellular Localizations
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Perikaryon. Cell projection, dendrite. Cell projection, axon. It is mainly cytoplasmic, where it is associated with microtubules.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Neurodegenerative Disorders
- Mammary Neoplasms
- Traditional Serrated Adenoma
- Neoplasm Metastasis
- Carcinoma
- Leukemia
- Cell Invasion
- Nerve Degeneration
- Cell Transformation, Neoplastic
Interacting Proteins
- ATP13A2
- BRMS1
- Cdc20
- CTNNB1
- CTTN
- Cttn
- CYLD
- EGFR
- MYD88
- PRKCA
Pathways
- Cell Migration
- Autophagy
- Transport
- Localization
- Cell Motility
- Cell Death
- Cell Cycle
- Cell Growth
- Histone Acetylation
- Cell Proliferation
- Tubulin Deacetylation
- Angiogenesis
- Pathogenesis
PTMs
- Acetylation
- Deacetylation
- Phosphorylation
- Ubiquitination
- Cleavage
- Dephosphorylation
Research Areas
- Breast Cancer
- Cancer
- Cell Cycle and Replication
- Chromatin Research
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HDAC6
bosterbio.com/bosterbio-gene-info-cards/HDAC6
References
PMID: 10220385 by Grozinger C.M., et al. Three proteins define a class of human histone deacetylases related to yeast Hda1p.
PMID: 11533236 by Amann J.M., et al. ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain.