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- Table of Contents
2 Citations
Facts about Histone deacetylase 2.
Histone deacetylases act via the formation of large multiprotein complexes. Types transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR.
Human | |
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Gene Name: | HDAC2 |
Uniprot: | Q92769 |
Entrez: | 3066 |
Belongs to: |
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histone deacetylase family |
EC 3.5.1.98; HD2; HDAC2; Histone Deacetylase 2; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1-associated factor 1
Mass (kDA):
55.364 kDA
Human | |
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Location: | 6q21 |
Sequence: | 6; NC_000006.12 (113933028..113971148, complement) |
Widely expressed; lower levels in brain and lung.
Nucleus. Cytoplasm.
PMID: 8917507 by Yang W.-M., et al. Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3.
PMID: 10545197 by Schmidt D.R., et al. Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4.
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