HARS2 Antibodies

AND HARS2 ELISA kits, HARS2 Proteins

Many biological assays use antibodies to detect HARS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HARS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HARS2 antibodies...

We validate the specificity of these antibodies to HARS2 by testing them on tissues known to express HARS2 positively and negatively. Browse below to find the HARS2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HARS2 Infographic by Boster Bio

All HARS2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HARS2 Antibody

Human, Mouse, Rat

$405
Cat # A07330
100ul

Anti-HARS2 Mouse Monoclonal Antibody [Clone ID: OTI5A9]

Human

Flow Cytometry, IF, IHC, WB

$523
Cat # M07330-1
100 µl

Anti-HARS2 Mouse Monoclonal Antibody [Clone ID: OTI5H2]

+12

Dog, Human, Monkey

Flow Cytometry, IHC, WB

$523
Cat # M07330
100 µl

HARS2 (NM_012208) Human Over-expression Lysate

Human

$628
Cat # LS023438
100 µg

HARS2 Overview

Facts about Histidine--tRNA ligase, mitochondrial.

HARS2 3D structure. Source: alphafold

Histidine--tRNA ligase, mitochondrial (HARS2)

Gene Information

Human
Gene Name:	HARS2
Uniprot:	P49590
Entrez:	23438

Family

Belongs to:

class-II aminoacyl-tRNA synthetase family

Alternative Names

EC 6.1.1; EC 6.1.1.21; HARSLprobable histidyl-tRNA synthetase, mitochondrial; HARS-related; HARSRhistidine tRNA ligase 2, mitochondrial (putative); HisRS; histidine translase; Histidine--tRNA ligase; Histidine--tRNA ligase-like; histidyl-tRNA synthetase 2, mitochondrial (putative); histidyl-tRNA synthetase-like; HO3histidine-tRNA ligase homolog

Molecular Weight

Mass (kDA):
56.888 kDA

Genomic Context


Human

Location:	5q31.3
Sequence:	5; NC_000005.10 (140691444..140699308)

Tissue Specificity

A high level expression is seen in the heart, kidney and skeletal muscle while a lower level expression is seen in the brain and liver.

Subcellular Localizations

Mitochondrion.

Diseases

Gonadal Dysgenesis Xx Type Deafness
Sensorineural Hearing Loss (disorder)
Learning Disorders
Congenital Abnormality
Gonadal Dysgenesis
Developmental Disabilities
Epilepsy
Immunologic Deficiency Syndromes

Usher Syndrome
Hiv Infections
Secondary Parkinson Disease

Interacting Proteins

AGTRAP

Pathways

Translation
Mitochondrial Translation

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HARS2

References

PMID: 7755634 by O'Hanlon T.P., et al. A novel gene oriented in a head-to-head configuration with the human histidyl-tRNA synthetase (HRS) gene encodes an mRNA that predicts a polypeptide homologous to HRS.

PMID: 21464306 by Pierce S.B., et al. Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome.