HAP1 Antibodies

AND HAP1 ELISA kits, HAP1 Proteins

Many biological assays use antibodies to detect HAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HAP1 antibodies...

We validate the specificity of these antibodies to HAP1 by testing them on tissues known to express HAP1 positively and negatively. Browse below to find the HAP1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HAP1 Infographic by Boster Bio

All HAP1 Products

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Product

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Specificity

Applications

Price

Anti-HAP1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A01658
0.1 mg

Anti-HAP1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A01658-3
100 μg/vial

Huntingtin Associated Protein 1 (HAP1) (NM_001079871) Human Over-expression Lysate

Human

$960
Cat # LS009001
100 µg

HAP1 Overview

Facts about Huntingtin-associated protein 1.

HAP1 3D structure. Source: alphafold

Huntingtin-associated protein 1 (HAP1)

Initially identified as neuronal protein that specifically associates with HTT/huntingtin and the binding is enhanced by an expanded polyglutamine repeat within HTT possibly affecting HAP1 interaction properties. The two HTT and HAP1 are involved in intracellular trafficking and HAP1 is proposed to connect HTT to motor proteins and/or transport cargos.

Seems to play a role in vesicular transport within neurons and axons like from early endosomes to late endocytic compartments and to promote neurite outgrowth. The vesicular transport function via association with microtubule-dependent transporters can be attenuated by association with mutant HTT.

Gene Information

Human
Gene Name:	HAP1
Uniprot:	P54257
Entrez:	9001

Family

Belongs to:

No superfamily

Alternative Names

HAP2huntingtin-associated protein 2; hHLP1; HIP5; HLP1; HLPHAP-1; huntingtin-associated protein 1; Neuroan 1

Molecular Weight

Mass (kDA):
75.506 kDA

Genomic Context


Human

Location:	17q21.2
Sequence:	17; NC_000017.11 (41717739..41734646, complement)

Tissue Specificity

Predominantly expressed in brain. Selectively expressed in neurons.

Subcellular Localizations

Cytoplasm. Cell projection, axon. Cell junction, synapse, presynapse. Cytoplasm, cytoskeleton. Cell projection, dendritic spine. Cell projection, dendrite. Lysosome. Endoplasmic reticulum. Mitochondrion. Nucleus. Cytoplasmic vesicle, autophagosome. Early endosome. Cell projection, growth cone. Cell projection, neuron projection. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Localizes to large nonmembrane-bound cytoplasmic bodies found in various types of neurons, called stigmoid bodies (STBs). Localization to neuronal processes and neurite tips is decreased by YWHAZ. In the nucleus