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- Table of Contents
Facts about Homeobox protein goosecoid.
In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the evolution of the entire tympanic ring. Goosecoid-expressing regions of the gastrulating mouse egg cylinder have organizer-like action when transplanted into Xenopus embryos.
Mouse | |
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Gene Name: | Gsc |
Uniprot: | Q02591 |
Entrez: | 14836 |
Belongs to: |
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paired homeobox family |
goosecoid homeobox; Goosecoid; GSC; homeobox protein goosecoid
Mass (kDA):
27.98 kDA
Mouse | |
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Location: | 12 E|12 54.32 cM |
Sequence: | 12; |
In early gastrulation, expressed in the dorsal lip. In later stages of development found in head, limbs and body wall. In the embryo, expressed in the postotic cranial neural crest cells, the frontonasal prominence, the first branchial arch and cleft, and specific regions of large joints.
PMID: 1352187 by Blum M., et al. Gastrulation in the mouse: the role of the homeobox gene goosecoid.
PMID: 9417125 by Danilov V., et al. Negative autoregulation of the organizer-specific homeobox gene goosecoid.