GRIP1 Antibodies

AND GRIP1 ELISA kits, GRIP1 Proteins

Many biological assays use antibodies to detect GRIP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GRIP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GRIP1 antibodies...

We validate the specificity of these antibodies to GRIP1 by testing them on tissues known to express GRIP1 positively and negatively. Browse below to find the GRIP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GRIP1 Infographic by Boster Bio

All GRIP1 Products

Product

Figures

Specificity

Applications

Price

Anti-GRIP1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A03167
0.1 mg

GRIP1 (NM_021150) Human Over-expression Lysate

Human

$960
Cat # LS023426
100 µg

GRIP1 Overview

Facts about Glutamate receptor-interacting protein 1.

GRIP1 3D structure. Source: alphafold

Glutamate receptor-interacting protein 1 (GRIP1)

May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons (PubMed:10197531). Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of this GRIA2 subunit toward recycling and membrane targeting (By similarity).

Gene Information

Human
Gene Name:	GRIP1
Uniprot:	Q9Y3R0
Entrez:	23426

Family

Belongs to:

No superfamily

Alternative Names

glutamate receptor interacting protein 1; glutamate receptor-interacting protein 1; GRIP; GRIP-1

Molecular Weight

Mass (kDA):
122.422 kDA

Genomic Context


Human

Location:	12q14.3
Sequence:	12; NC_000012.12 (66347431..67069265, complement)

Subcellular Localizations

Cytoplasmic vesicle. Perikaryon. Cell projection, dendrite. Cytoplasm. Endomembrane system; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, postsynaptic density. Endoplasmic reticulum membrane; Peripheral membrane protein. Membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in postsynaptic plasma membrane and postsynaptic densities.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Depressive Disorder
Neoplasms
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Bulla
Tissue Adhesions
Carcinoma
Cryptophthalmos Syndrome
Liver Carcinoma
Schizophrenia

Nervousness
Syndactyly
Cryptophthalmos
Hereditary Diseases
Endometrial Polyp
Congenital Absence
Obesity

Interacting Proteins

ESR1
IRF3
PRLHR
PSMB9

Pathways

Localization
Synaptic Transmission
Methylation
Endocytosis
Cell Proliferation
Transport
Chromatin Remodeling
Cell Growth
Receptor Recycling
Receptor Clustering
Receptor Internalization
Pathogenesis
Hyperphosphorylation

Secretion
Cell Migration
Protein Targeting
Spermatogenesis
Cell Differentiation
Receptor Transactivation
Proteolysis

PTMs

Phosphorylation
Methylation
Acetylation
Reduction
Palmitoylation
Ubiquitination

Sumoylation
Cleavage
Deacetylation
Oxidation
Dephosphorylation
Ribosylation

Research Areas

Cancer
Neuronal Cell Markers
Neurotransmission
Transcription Factors and Regulators

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRIP1

References

PMID: 10197531 by Brueckner K., et al. EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains.

PMID: 11641419 by Lin S.H.S., et al. The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy- 5-methylisoxazole-4-propionic acid receptor clustering.