Glycophorin-C Antibodies

AND GYPC ELISA kits, Glycophorin-C Proteins

Many biological assays use antibodies to detect Glycophorin-C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Glycophorin-C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Glycophorin-C antibodies...

We validate the specificity of these antibodies to Glycophorin-C by testing them on tissues known to express GYPC positively and negatively. Browse below to find the GYPC antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GYPC Infographic by Boster Bio

All GYPC Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CD236 GYPC Antibody

5 Q&As

Human

IHC

$399
Cat # A05974
100μl

Anti-Glycophorin C GYPC Monoclonal Antibody

1 Q&As

Human

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M05974
100 μl

Glycophorin C (GYPC) (NM_016815) Human Recombinant Protein

$1249
Cat # PROTP04921
20 µg

Glycophorin C (GYPC) (NM_002101) Human Over-expression Lysate

Human

$628
Cat # LS002995
100 µg

GYPC Overview

Facts about Glycophorin-C.

GYPC 3D structure. Source: alphafold

Glycophorin-C (GYPC)

This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely found within the extracellular domain.

Glycophorin-C plays an significant role in regulating the stability of red cells. .

Gene Information

Human
Gene Name:	GYPC
Uniprot:	P04921
Entrez:	2995

Family

Belongs to:

glycophorin-C family

Alternative Names

CD236 antigen; CD236; CD236R; GE; GLPC; glycoconnectin; glycophorin C (Gerbich blood group); glycophorin-C; glycophorin-D; Glycoprotein beta; GPCMGC126191; GPD; GYPD; MGC117309; MGC126192; PAS-2; PAS-2'; Sialoglycoprotein D

Molecular Weight

Mass (kDA):
13.811 kDA

Genomic Context


Human

Location:	2q14.3
Sequence:	2; NC_000002.12 (126655935..126696675)

Tissue Specificity

Glycophorin-C is expressed in erythrocytes. Glycophorin-D and IsoGPC are ubiquitously expressed.

Subcellular Localizations

Cell membrane; Single-pass type III membrane protein. Linked to the membrane via band 4.1.

Diseases

Malaria
Cell Invasion
Malaria, Falciparum
Elliptocytosis, Hereditary
Chromosomal Deletion
Transfusion Reaction
Hemolytic Disorder
Thalassemia
Anemia
Polyploidy
Acute Lymphocytic Leukemia
Blood Group Incompatibility

Nervousness
Erythroblastosis, Fetal
Leukemia
Attention Deficit Hyperactivity Disorder
Hemoglobinopathies
L1 Acute Lymphoblastic Leukemia

Pathways

Translation
Transport
Brain Development

PTMs

Glycosylation

Research Areas

Cancer
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GYPC

References

PMID: 2416746 by Colin Y., et al. Isolation of cDNA clones and complete amino acid sequence of human erythrocyte glycophorin C.

PMID: 3606576 by High S., et al. Human erythrocyte membrane sialoglycoprotein beta. The cDNA sequence suggests the absence of a cleaved N-terminal signal sequence.