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GTF2IRD1 Antibodies
AND GTF2IRD1 ELISA kits, GTF2IRD1 Proteins
Many biological assays use antibodies to detect GTF2IRD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GTF2IRD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GTF2IRD1 antibodies...
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GTF2IRD1 Infographic by Boster Bio
All GTF2IRD1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
WB
$523
Cat # M04254
100 µl
Cat # M04254
100 µl
GTF2IRD1 Overview
Facts about General transcription factor II-I repeat domain-containing protein 1.
General transcription factor II-I repeat domain-containing protein 1 (GTF2IRD1)
Might be a transcription regulator involved in cell-cycle development and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation.
May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1).
Gene Information
| Human | |
|---|---|
| Gene Name: | GTF2IRD1 |
| Uniprot: | Q9UHL9 |
| Entrez: | 9569 |
Family
| Belongs to: |
|---|
| TFII-I family |
Alternative Names
BEN; CREAM1; general transcription factor II-I repeat domain-containing protein 1; General transcription factor III; GTF2I repeat domain containing 1; GTF2I repeat domain-containing protein 1; GTF3GTF2I repeat domain-containing 1; hMusTRD1alpha1; muscle TFII-I repeat domain-containing protein 1 alpha 1; Muscle TFII-I repeat domain-containing protein 1; MusTRD1; MusTRD1/BEN; MUSTRD1general transcription factor 3; RBAP2WBSCR12binding factor for early enhancer; Slow-muscle-fiber enhancer-binding protein; USE B1-binding protein; WBS; WBSCR11; Williams-Beuren syndrome chromosomal region 11 protein;
Molecular Weight
Mass (kDA):
106.057 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q11.23 |
| Sequence: | 7; NC_000007.14 (74453906..74603070) |
Tissue Specificity
Highly expressed in adult skeletal muscle, heart, fibroblast, bone and fetal tissues. Expressed at lower levels in all other tissues tested.
Subcellular Localizations
Nucleus.
Diseases
- Williams Syndrome
- Haploinsufficiency
- Stenosis
- Hereditary Diseases
- Craniofacial Abnormalities
- Aortic Valve Stenosis
- Developmental Disabilities
- Anxiety Disorders
- Cognition Disorders
- Supravalvular Aortic Stenosis
- Malnutrition
- Congenital Anomaly Of Face
Interacting Proteins
- ATF7IP
- DCAF6
- Homez
- INTS12
- MBD3L1
- Nap1l2
- PKP1
- Setd6
- ZMYM2
- Zmym3
Pathways
- Pathogenesis
- Cognition
- Cell Cycle
- Social Behavior
- Angiogenesis
- Transport
- Response To Stress
- Developmental Process
- Stem Cell Differentiation
- Brain Development
- Immune Response
- Histone Modification
- Oxidative Phosphorylation
PTMs
- Sumoylation
- Ubiquitination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GTF2IRD1
bosterbio.com/bosterbio-gene-info-cards/GTF2IRD1
References
PMID: 9774679 by O'Mahoney J.V., et al. Identification of a novel slow-muscle-fiber enhancer binding protein, MUSTRD1.
PMID: 10198167 by Osborne L.R., et al. Identification of a putative transcription factor gene (WBSCR11) that is commonly deleted in Williams-Beuren syndrome.