GSTZ1 Antibodies

AND GSTZ1 ELISA kits, GSTZ1 Proteins

Many biological assays use antibodies to detect GSTZ1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GSTZ1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GSTZ1 antibodies...

We validate the specificity of these antibodies to GSTZ1 by testing them on tissues known to express GSTZ1 positively and negatively. Browse below to find the GSTZ1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GSTZ1 Infographic by Boster Bio

All GSTZ1 Products

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Glutathione Transferase zeta 1 (GSTZ1) (NM_001513) Human Recombinant Protein

$813
Cat # PROTO43708
20 µg

Anti-Glutathione Transferase zeta 1 (GSTZ1) Mouse Monoclonal Antibody [Clone ID: OTI6A10]

Human, Mouse, Rat

$523
Cat # M03948
100 µl

GSTZ1 Overview

Facts about Maleylacetoacetate isomerase.

GSTZ1 3D structure. Source: alphafold

Maleylacetoacetate isomerase (GSTZ1)

Bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4- nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with T- butyl and cumene hydroperoxides.

Can catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. .

Gene Information

Human
Gene Name:	GSTZ1
Uniprot:	O43708
Entrez:	2954

Family

Belongs to:

GST superfamily

Alternative Names

EC 2.5.1.18; EC 5.2.1.2; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; Glutathione S-transferase zeta 1; glutathione transferase zeta 1; GSTZ1-1maleylacetoacetate isomerase; MAAIglutathione S-aryltransferase; MAI; maleylacetone isomerase; MGC2029; S-(hydroxyalkyl)glutathione lyase

Molecular Weight

Mass (kDA):
24.212 kDA

Genomic Context


Human

Location:	14q24.3
Sequence:	14; NC_000014.9 (77321002..77331597)

Tissue Specificity

Mostly expressed in liver followed by kidney, skeletal muscle and brain. Also expressed in melanocytes, synovium, placenta, breast and fetal liver and heart.

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Acidosis
Acidosis, Lactic
Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Dysequilibrium Syndrome
Malignant Neoplasm Of Lung
Parkinson Disease
Lung Neoplasms
Malignant Neoplasm Of Urinary Bladder
Hepatotoxicity
Tyrosinemias

Leukopenia
Tyrosinemia, Type I
Bladder Neoplasm
Metabolic Diseases
Cholangiocarcinoma
Disease Of Adrenal Medulla
Malnutrition

Interacting Proteins

NCK1

Pathways

Dna Repair
Excretion
Pathogenesis
Dna Methylation
Conjugation
Localization
Liver Development
Methylation
Dna Hypermethylation

Cellular Senescence
Aging
Senescence
Cell Death

PTMs

Reduction

Methylation

Decarboxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GSTZ1

References

PMID: 9417084 by Fernandez-Canon J.M., et al. Characterization of a fungal maleylacetoacetate isomerase gene and identification of its human homologue.

PMID: 9396740 by Board P.G., et al. Zeta, a novel class of glutathione transferases in a range of species from plants to humans.